A series of (4-(7-chloroquinolin-4-yl)piperazin-1-yl)(substitutedphenyl)methanones were prepared via multistep synthesis which involved acrylation without base, cyclisation, hydrolysis, decarboxylation, electrophilic ...

A new series of pyrrolobenzodiazepine derivatives containing 1,2,3-triazoles moiety has been designed and developed via Cu(I)-catalyzed azide-alkyne cycloaddition reaction, click chemistry synthetic aspect under microwave ...

Ten new non-nucleophilic base (DBU) catalyzed oxazolone-bearing pyrazole derivatives were created to treat infectious diseases caused by bacterial, mycobacterial strains, and cancerous cell lines. Compounds 7b and 7c showed ...

A novel series of benzofuran bearing thiazole hybrids were synthesized by the multistep reaction approach. All synthesized molecules were selected by the National Cancer Institute, USA for one-dose anticancer activity ...

We report here the synthesis of different substituted tetrahydropyridopyrazine derivatives. This approach of synthesis has been designed in a way that in first simple chloro-amine coupling as an alternative of Buchwald ...