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Browsing by Subject "cancer"

Browsing by Subject "cancer"

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  • Cell-Penetrable Peptide-Conjugated FADD Induces Apoptosis and Regulates Inflammatory Signaling in Cancer Cells 
    Ranjan, Kishu; Waghela y, Bhargav N; Vaidya, Foram U (2020-09-19)
    Dysregulated expression of Fas-associated death domain (FADD) is associated with the impediment of various cellular pathways, including apoptosis and inflammation. The adequate cytosolic expression of FADD is critical ...
  • Evaluation of antimitotic activity of herbal extracts using plant‑based model systems and their cytotoxic potential against human colon carcinoma cells 
    Parmar, Mayur P; Waghela, Bhargav N; Vaidya, Foram U; Pathak, Chandramani; Parmar, Dipak V (2022-01-18)
    Objective: The aim of this study was to screen plant extracts for antimitotic activity using Vigna radiata germination inhibition assay, followed by Allium cepa root tip assay and evaluation of their cytotoxic potential ...
  • PNMA family 
    Pang, S. W.; Lahiri, Chandrajit; Poh, C. L.; Tan, Kuan Onn (Elsevier, 2018)
    Paraneoplastic Ma Family (PNMA) comprises a growing number of family members which share relatively conserved protein sequences encoded by the human genome and is localized to several human chromosomes, including the ...
  • A side-effect free method for identifying cancer drug targets 
    Ashraf, M. I.; Ong, S. K.; Mujawar, s.; Pawar, S.; More, P.; Paul, S.; Lahiri, Chandrajit (Nature, 2018)
    Identifying effective drug targets, with little or no side effects, remains an ever challenging task. A potential pitfall of failing to uncover the correct drug targets, due to side effect of pleiotropic genes, might lead ...
  • Targeting ferroptosis pathways: a novel strategy for cancer therapy 
    Maru, Devangkumar; Hothi, Akhil; Bagariya, Chintan; Kumar, Anmol (Bentham Science Publishers/ Current Cancer Drug Targets, 2022-03-01)
    Ferroptosis is an iron-dependent nonapoptotic kind of regulated cell death resulting from the destruction of redox balance in the cytosol. Unlike apoptosis, ferroptosis is caused by an increase in intracellular iron and ...