Sister Institute on the campus Affiliated to Saurashtra University, Rajkot http://10.9.150.37:8080/dspace//handle/atmiyauni/239 2026-05-10T15:05:43Z 2026-05-10T15:05:43Z Akbari, P.M Shah, V.R. http://10.9.150.37:8080/dspace//handle/atmiyauni/2205 2025-01-01T11:26:08Z 2019-01-01T00:00:00Z

Synthesis, Characterization and Biological Evaluation of Ethyl-4'-(cyclopropane carboxamido-N-yl)-5-ary-3-oxo-3,4,5,6- tetrahydro-biphenyl-4-carboxylate Akbari, P.M; Shah, V.R. A series of new substituted cyclohexenone derivatives have been synthesized by the reaction of various substituted chalcones with ethylacetoacetate. Some new N-(4-(3-aryl-acryloyl)phenyl)cyclopropane carboxamide were prepared by Claisen-Schmidt condensation method in presence of sodium hydroxide in ethanol solvent under stirring. The synthesized compounds were characterized by their spectral (IR, NMR, Mass) data and screened for their antimicrobial activities against Gram-positive and Gram-negative bacteria by using standard antimicrobial drugs.

2019-01-01T00:00:00Z Sanghani, Yogesh J. Koradiya, Suresh B. Jilariya, Krushnakumar J. http://10.9.150.37:8080/dspace//handle/atmiyauni/2194 2025-01-01T10:58:27Z 2020-01-01T00:00:00Z

Synthesis, Characterization and in vitro Antimicrobial Evaluation of Pyrazole Based Oxothiazolidine Hybrids Sanghani, Yogesh J.; Koradiya, Suresh B.; Jilariya, Krushnakumar J. In this work, pyrazole based oxothiazolidine hybrids, 4-{4-[2-(1- phenyl-3-(substituted)phenyl-1H-pyrazol-4-yl)-4-oxo-thiazolidin-3- yl]-phenyl}-morpholin-3-one (11a-l) were synthesized using molecular hybridization approach through Vilsmeier-Haack reaction. The titled compounds 11a-l were characterized by using elemental analysis, IR, 1H NMR and mass spectral studies. The antibacterial activity of 11a-l was evaluated in vitro by agar cup plate method against B. cocous, B. subtillis, E. coli and P. vulgaris. The antifungal activity of compounds 11a-l was evaluated in vitro by agar based disk diffusion method against A. niger. The results of antibacterial and antifungal evaluation were reported in terms of zone of inhibition measured in mm. The synthesized compounds 11a-l exhibited moderate to good antibacterial and antifungal potential. Compound 4-{4-[2-(1-phenyl-3-(2-methoxyphenyl) phenyl-1H-pyrazol-4-yl)-4-oxo-thiazolidin-3-yl]-phenyl}- morpholin-3-one (11h) emerged as a most potent antimicrobial agent displaying zone of inhibition 21, 20, 21, 24 and 20 mm against B. cocous, B. subtillis, E. coli, P. vulgaris and A. niger, respectively.

2020-01-01T00:00:00Z Lungariya, Amisha Mehta, Hemangi Patadia, Apexa http://10.9.150.37:8080/dspace//handle/atmiyauni/998 2023-05-18T02:33:41Z 2015-08-01T00:00:00Z

Isolation and screening of moderate halophiles for industrially important hydrolytic enzymes Lungariya, Amisha; Mehta, Hemangi; Patadia, Apexa Halophiles are the salt loving organisms, which are found to survive in wide range of salt concentration. Based on their salt requirement, halophiles are categorized into different categories; 1. Slight, 2. Moderate, 3. Extreme. Moderate halophiles were isolated from Jamnagar Vadinar Bandar area. Total 16 isolates were obtained on N-agar plates containing various salt concentrations. These organisms were exploited for various hydrolytic enzyme activity i.e.; amylase, lipase, caseinase etc. Among 16 isolates, 9 were amylase positive, 12 were lipase positive, 13 were caseinase positive. Identification of these isolates was on the basis of morphology, physiology, biochemical activity. Further research on purification of one of these enzymes is in progress.

2015-08-01T00:00:00Z Devmurari, Vishvraj V. Patel, Poojaben P. Jadeja, Rajeshreeba A. Bhadaniya, Cameykumari P. Aghara, Priti P. Patel, Anilkumar S. Tala, Satishkumar D. Savant, Mahesh M. Ladva, Kartik D. Nariya, Pankajkumar B. http://10.9.150.37:8080/dspace//handle/atmiyauni/990 2023-05-17T05:07:47Z 2021-06-30T00:00:00Z

Steroid and fatty acid contents from the leaves of Carica Papaya Devmurari, Vishvraj V.; Patel, Poojaben P.; Jadeja, Rajeshreeba A.; Bhadaniya, Cameykumari P.; Aghara, Priti P.; Patel, Anilkumar S.; Tala, Satishkumar D.; Savant, Mahesh M.; Ladva, Kartik D.; Nariya, Pankajkumar B. Aim: To extract and identify the non-polar entities from the leaves of Carica papaya, a plant used for medicinal purpose as folk medicine. Materials and methods: Petroleum ether extract of the Carica papaya leaves was used for this study. Saponification process and methylation process was performed to separate fatty acids and unsaponifiable matters. Phytochemical constituents were separated using chemical process and separated fractions were analyzed by thin layer chromatography (TLC) and gas chromatography coupled with mass spectroscopy (GC-MS). Results: The chemical composition of the steroids, triterpenoids and fatty acid methyl esters (FAMEs) in leaves of Carica papaya, which were analyzed by gas chromatography coupled with mass spectroscopy (GC-MS). A total of 15 fatty acid components were identified in saponifiable matter, from unsaponifiable portion 2 steroids (campesterol, β- or γ-sitosterol), 1 triterpene (squalene), and 1 diterpene (phytol) were identified. Conclusions: The results indicate that the extract is rich in non-polar compounds. In this study, GC-MS method is at the central focus for identification of these phytoconstituents. The current method can be used for direct analysis of non-polar entities of plant material. We are grateful to the Department of Chemistry, Atmiya University and Shri M. & N. Virani Science College, Rajkot for providing laboratory and other required facilities.

2021-06-30T00:00:00Z