DSpace Repository

Formulation and Development of Microemulsion Based Gel (Mbg) of Ibuprofen for Topical Drug Delivery

Show simple item record

dc.contributor.author Shah, Akash
dc.contributor.author Vyas, Kalyani
dc.contributor.author Aviya, Ketan
dc.contributor.author Jivani, Pankti
dc.contributor.author Dobariya, Vishal
dc.contributor.author Patel, Jaydeep
dc.contributor.author Garala, Kevin
dc.date.accessioned 2023-05-27T07:29:52Z
dc.date.available 2023-05-27T07:29:52Z
dc.date.issued 2013
dc.identifier.citation Akash Shah, Kalyani Vyas, Ketan Aviya et al., Formulation and Development of Microemulsion Based Gel (Mbg) of Ibuprofen for Topical Drug Delivery. Inventi Rapid: NDDS, 2013(2):1-6, 2013. en_US
dc.identifier.issn 0976-3791
dc.identifier.uri http://10.9.150.37:8080/dspace//handle/atmiyauni/1142
dc.description.abstract The aim of the present study was to formulate an Ibuprofen loaded microemulsion based gel (MBG) for the topical delivery. The oil phase selected for the preparation of stable microemulsion was IsoPropyl Myristate (IPM). Tween-80 and PEG 400 were selected as surfactant and co-surfactant respectively. For the ease of application microemulsion was gelled by using carbopol 940. The optimized MBG was evaluated for pH measurements, spreadability, swelling index study, drug content and in vitro permeation study. The in-vitro skin permeation was carried out in pH 7.4 phosphate buffer on excised mice skin using franz-diffusion cell for 4 h and was compared with a conventional gel formulation. The results showed that release of drug from MBG was found to be 97.78% as compared to 79% from conventional gel formulation. The study also showed flux value 0.453μg/cm2/min for MBG as compared to 0.353 μg/cm2/min which was found in the case of conventional gel. Hence MBG is the promosing alternative for the topical delivery of the drug. en_US
dc.language.iso en en_US
dc.publisher Inventi Journals en_US
dc.title Formulation and Development of Microemulsion Based Gel (Mbg) of Ibuprofen for Topical Drug Delivery en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account