Synthesis and Evaluation of Some Novel Substituted 1, 3, 4- Oxadiazole and Pyrazole Derivatives for Antifungal Activity

Abstract

A series of 1,3,4-oxadiazole and pyrazole derivatives have been synthesized and evaluated for antifungal activity. The structures of synthesized compounds were confirmed by IR, 1H NMR, Mass and CHN analysis. These compounds have shown promising antifungal activity when compared with the standard drug griseofulvin by cup-plate agar diffusion method using sabouraud-dextrose agar.