DSpace Repository

Development and Validation of High-Performance Thin-Layer Chromatography Method for Determination of Nebivolol and Amlodipine besylate in Combined Dosage Forms

Show simple item record

dc.contributor.author Patel, Samixa
dc.contributor.author Patel, Shweta
dc.contributor.author Patel, Jignesh
dc.contributor.author Patel, Paresh
dc.date.accessioned 2023-05-29T05:08:52Z
dc.date.available 2023-05-29T05:08:52Z
dc.date.issued 2010-01
dc.identifier.citation Patel, S. ,Patel, S. ,Patel, J. ,Patel, P. (2010). Development and Validation of High-Performance Thin-Layer Chromatography Method for Determination of Nebivolol and Amlodipine besylate in Combined Dosage Forms. Journal of Pharmacy Research, 4(1), ISSN: 0974-6943, Available online through www.jpronline.info en_US
dc.identifier.issn 0974-6943
dc.identifier.uri http://10.9.150.37:8080/dspace//handle/atmiyauni/1147
dc.description The authors are greatly thankful to Torrent Pharmaceutical Ltd, Indrad, India for providing gift sample of NEB and AML and S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva for providing all the facilities to carry out the work. en_US
dc.description.abstract The manuscript describes validated High-Performance Thin-Layer Chromatography (HPTLC) method for the estimation of Nebivolol (NEB) and Amlodipine (AML) in combined dosage form. The HPTLC separation was achieved on an aluminium-backed layer of silica gel 60F254 using chloroform-methanol-toluene-ammonia (8+ 1.8+ 1+ 0.3, v/v/v/v/) as mobile phase. Quantitation was achieved with UV detection at 273 nm over the concentration range 400-1000 ng/spot and 200 – 800 ng/spot for Nebivolol and Amlodipine, respectively with mean recovery of 100.3 ± 0.76 and 100.5 ± 0.92 % for Nebivolol and Amlodipine by HPTLC method. These method were found to be Simple, sensitive, accurate, precise, reproducible, and economical can be applicable for the simultaneous determination of Nebivolol and Amlodipine in combined dosage form. en_US
dc.language.iso en en_US
dc.publisher Journal of Pharmacy Research en_US
dc.subject Nebivolol en_US
dc.subject Amlodipine besylate en_US
dc.subject HPTLC en_US
dc.title Development and Validation of High-Performance Thin-Layer Chromatography Method for Determination of Nebivolol and Amlodipine besylate in Combined Dosage Forms en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account