Determination of ETORICOXIB in Bulk Formulations by RP-HPLC methods

Bansal, Aayushi

dc.contributor.author	Bansal, Aayushi
dc.date.accessioned	2023-05-29T06:28:57Z
dc.date.available	2023-05-29T06:28:57Z
dc.date.issued	2022
dc.identifier.citation	Bansal Auyushi, 2022, Determination of ETORICOXIB in Bulk Formulations by RP-HPLC methods, World Journal of Pharmaceutical Research, Volume 11, Issue 15, 1128-1136. , ISSN 2277– 7105,	en_US
dc.identifier.issn	2277– 7105
dc.identifier.uri	http://10.9.150.37:8080/dspace//handle/atmiyauni/1160
dc.description	I am deeply indebted to Akums Drugs and Pharmaceuticals Ltd. for letting me to conduct my research work. Words cannot express my appreciation to my family and friends for their constant support and help.	en_US
dc.description.abstract	For the determination of Etoricoxib in bulk formulations a rapid, selective and simple RP-HPLC method was formed and used, by optimizing stationary phase, composition of mobile phase and other parameters. Study was performed on RP- C-18 (250 x 4.6 mm), 5 µm column (Symmetry, Waters) with the mobile phase Acetonitrile: Phosphate buffer in the ratio of 70:30 v/v. At a flow rate of 1 ml/ min, the mobile phase was pumped and the detection was monitored at 220 nm. Short retention time was observed of the drug i.e. 9.589 min. The calibration curve was linear from 70ppm to 130 ppm and correlation coefficient of 0.998144. The intra-day precision (%RSD) was 0.99 and inter-day precision (% RSD) was in the range 0.99 to 1.21. The assay was found to be 99.28 %. The above method was successfully used for the assay of etoricoxib in bulk formulations	en_US
dc.language.iso	en	en_US
dc.publisher	World Journal of Pharmaceutical Research	en_US
dc.subject	Etoricoxib	en_US
dc.subject	RP-HPLC	en_US
dc.subject	Assay	en_US
dc.subject	Bulk formulation	en_US
dc.title	Determination of ETORICOXIB in Bulk Formulations by RP-HPLC methods	en_US
dc.type	Article	en_US