Microfluidic Organ-On-A-Chip Models of Human organs in Drug Discovery

Abstract

Recent years have seen a rise in interest in microfluidics phenomena as scientists have taken advantage of their special qualities to create better design options. Over the past few years, there has been an increase in interest in the application of microfluidic phenomena for tissue engineering and drug testing. Researchers have developed technologies that enable them to model the properties and functions of a wide range of organs on a microscale chip, mimicking the processes that occur in actual creatures. This article presents a logical approach to the subject and provides an overview of the latest technologies that are appropriate for organ-on-a-chip systems. The construction of synthetic or natural small tissues that can mimic physiological processes found in the human body is made possible by the use of microfluidic chips. They also maintain the tissue-specific functioning and control the microenvironments of individual cells. Advances in tissue engineering and microfabrication have allowed for the construction of organ-on-a-chips (OoCs), which have allowed researchers to conduct next-generation experiments and study human illness. Investigations into the effects of drugs on the human body are also being conducted. These abstract aims to provide an overview of the different Operating Systems (OoCs) components and help choose an OoC that is tailored to a certain application. If researchers have a greater understanding of the various components that make up OoCs, they can build applications in these sectors that are more effective and efficient.