Derivatives of 5-oxo-imidazoline exhibited good therapeutic activity, with a view of getting to synthesis 2-{[(4'-arylidine-5'-oxo-2'-phenyl)imidazolyl]-1'-yl}-3-(4-hydroxyphenyl) propanoic acids (1a–1n) have been synthesized, all the derivatives were undergone characterized by IR, 1H NMR and Mass spectral characterization methods. All the synthesized compounds (1a–1n) were evaluated for their antimicrobial activity at 40 μg concentration.
