Abstract:
A series of tetracyclic thiazepine based pyrazoles (6a-j) have been synthesized and evaluated for antibacterial and antifungal activities. The newly synthesized compounds have been characterized by IR, 1 H & 13 C NMR, mass and elemental analyses. Compounds 6b (2-OCH3 ) and 6c (4-OCH3 ) have shown promising antibacterial, and 6g (3-NO2 ), 6f (2-NO 2 ) and 6d (3,4-diOCH 3 ) exhibited excellent an antifungal activity against standard drugs.
