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Synthesis of Substituted 4-(4-((3-Nitro-2-oxo-2H-chromene-4-yl)amino)phenyl)morpholine-3-one Coumarin Derivatives

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dc.contributor.author Sanghani, Yogesh J.
dc.contributor.author Koradiya, Suresh B.
dc.contributor.author Patel, Anilkumar S.
dc.date.accessioned 2024-11-17T07:21:09Z
dc.date.available 2024-11-17T07:21:09Z
dc.date.issued 2019
dc.identifier.citation Sanghani, Y. J., Koradiya, S. B. and Patel, A. S. (2019). Synthesis of Substituted 4-(4-((3-Nitro-2-oxo-2H-chromene-4-yl)amino)phenyl)morpholine-3-one Coumarin Derivatives. Asian Journal of Chemistry, 31(7), 1461-1464. en_US
dc.identifier.uri http://10.9.150.37:8080/dspace//handle/atmiyauni/1596
dc.description.abstract A series of novel 4-(4-amino phenyl) morpholine-3-one substituted coumarin derivatives have been prepared by chloramine coupling reaction and were identified. The novel synthetic route involves nucleophilic substitution reaction of 4-chloro-3-nitro-2H-chromene-2-one with 4-(4-amino phenyl)morpholine-3-one. Due to the presence of nitro group in coumarin derivatives make substitution reaction easy and convenient at low temperature. Using DMF as solvent and K2 CO3 as base various substituted 4-(4-((3-nitro-2-oxo-2H-chromen-4-yl)amino)phenyl)morpholine-3-one derivatives (YS-1 to YS-10) can be obtain in good yield and high purity. Structural characterization of all synthesized compound was done by NMR, Mass and IR spectra en_US
dc.language.iso en en_US
dc.publisher Asian Journal of Chemistry en_US
dc.relation.ispartofseries ;31(7), 1461-1464
dc.subject 4-Chloro-3-nitro-2H-chromene-2-one en_US
dc.subject 4-(4-Amino phenyl)morpholine-3-one en_US
dc.subject 4-Hydroxy coumarin en_US
dc.title Synthesis of Substituted 4-(4-((3-Nitro-2-oxo-2H-chromene-4-yl)amino)phenyl)morpholine-3-one Coumarin Derivatives en_US
dc.type Article en_US


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