Synthesis and in vitro antidiabetic screening of novel dihydropyrimidine derivatives

Lalpara, J. N.; Vachhani, M. D.; Hadiyal, S. D.; Goswami, S.; Dubal, G. G.

dc.contributor.author	Lalpara, J. N.
dc.contributor.author	Vachhani, M. D.
dc.contributor.author	Hadiyal, S. D.
dc.contributor.author	Goswami, S.
dc.contributor.author	Dubal, G. G.
dc.date.accessioned	2024-11-18T06:50:14Z
dc.date.available	2024-11-18T06:50:14Z
dc.date.issued	2021-03-23
dc.identifier.citation	Lalpara, J. N., Vachhani, M. D., Hadiyal, S. D., Goswami, S., & Dubal, G. G. (2021). Synthesis and in vitro antidiabetic screening of novel dihydropyrimidine derivatives. Russian Journal of Organic Chemistry, 57, 241-246	en_US
dc.identifier.uri	http://10.9.150.37:8080/dspace//handle/atmiyauni/1619
dc.description.abstract	A series of N-substituted-6-methyl-4-{4-[5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl]methoxyphenyl}-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamides have been synthesized by the condensation of newly synthesized {4-[5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzaldehyde with variously substituted acetoacetanilides and urea in the presence of ethanol. The synthesized compounds have been characterized by 1H, 13C NMR, IR spectroscopy, and mass spectrometry. All Search Log in synthesized compounds were evaluated for in vitro antidiabetic activity using the α-amylase inhibition assay with the 3,5-dinitrosalicylic acid (DNSA) reagen	en_US
dc.language.iso	en	en_US
dc.publisher	Pleiades Publishing, Ltd. /Russian Journal of Bioorganic Chemistry	en_US
dc.relation.ispartofseries	;57, 241-246
dc.subject	vitro	en_US
dc.subject	antidiabetic screening	en_US
dc.subject	dihydropyrimidine	en_US
dc.subject	derivatives	en_US
dc.title	Synthesis and in vitro antidiabetic screening of novel dihydropyrimidine derivatives	en_US
dc.type	Article	en_US