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Phenylboronic acid catalyzed synthesis of polysubstituted 1,4-dihydropyridine derivatives as promising antioxidant agents correlated with molecular docking

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dc.contributor.author Pansuriya, K.
dc.contributor.author Lalpara, J. N.
dc.contributor.author Hadiyal, S. D.
dc.contributor.author Dhaduk, B. B.
dc.contributor.author Dubal, G. G
dc.date.accessioned 2024-11-18T11:29:57Z
dc.date.available 2024-11-18T11:29:57Z
dc.date.issued 2022
dc.identifier.citation Pansuriya, K., Lalpara, J. N., Hadiyal, S. D., Dhaduk, B. B., & Dubal, G. G. (2022). Phenylboronic acid catalyzed synthesis of polysubstituted 1, 4-dihydropyridine derivatives as promising antioxidant agents correlated with molecular docking. Chemical Data Collections, 42, 100946. en_US
dc.identifier.uri http://10.9.150.37:8080/dspace//handle/atmiyauni/1649
dc.description.abstract A series of polysubstituted 1, 4-dihydropyridines (4a-i) were designed and developed using Ph-B (OH) 2 catalyst. Further, compounds were confirmed by various spectroscopic techniques. After that all compounds were studied for molecular docking against the human peroxidase enzyme (1PRX). Results of docking revealed that many compounds exhibited low binding score. To get a reference from the docking study, all synthesized molecules were evaluated for in vitro antioxidant assay using DPPH, H 2 O 2 … en_US
dc.language.iso en en_US
dc.publisher Chemical Data Collections en_US
dc.subject 1,4-dihydropyridine en_US
dc.subject Boronic acid catalyzed en_US
dc.subject Antioxidants en_US
dc.subject Molecular docking en_US
dc.subject Hantzsch synthesis en_US
dc.title Phenylboronic acid catalyzed synthesis of polysubstituted 1,4-dihydropyridine derivatives as promising antioxidant agents correlated with molecular docking en_US
dc.type Article en_US


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