New 1,3,4-Oxadiazole based Schiff base Derivatives: Synthesis, Characterization and Antibacterial Activity Along With in Silico Studies

Lalpara, J. N.; Hadiyal, S. D.; Dhalani, J. M.; Dubal, G. G.

dc.contributor.author	Lalpara, J. N.
dc.contributor.author	Hadiyal, S. D.
dc.contributor.author	Dhalani, J. M.
dc.contributor.author	Dubal, G. G.
dc.date.accessioned	2024-11-19T04:58:08Z
dc.date.available	2024-11-19T04:58:08Z
dc.date.issued	2021
dc.identifier.citation	Lalpara , J. N., Hadiyal , S. D., Dhalani, J. M. and Dubal , G. G. (2021). New 1,3,4-Oxadiazole based Schiff base Derivatives: Synthesis, Characterization and Antibacterial Activity Along With in Silico Studies. European chemical bulletin, 10(3), 139-146	en_US
dc.identifier.uri	http://10.9.150.37:8080/dspace//handle/atmiyauni/1658
dc.description.abstract	A series of novel 1,3,4-oxadiazole based Schiff base derivatives were designed and synthesized using the efficient strategy with excellent yields. Synthesized molecules evaluated in vitro antibacterial studies in contradiction of microorganisms, namely Escherichia coli, Klebsiella pneumoniae, Bacillus subtilis, and Bacillus megaterium. The bioassay result revealed that most of tested compounds good to moderate inhibition against microorganisms. Some among them show excellent inhibitory effects towards the Gram-positive and Gram-negative bacteria. Besides, the drug-likeness, lipophilicity and cytotoxicity	en_US
dc.language.iso	en	en_US
dc.publisher	European chemical bulletin	en_US
dc.relation.ispartofseries	;10(3), 139-146
dc.subject	Schiff base	en_US
dc.subject	1,3,4-oxadiazole	en_US
dc.subject	antimicrobial	en_US
dc.subject	drug-likeness	en_US
dc.subject	cytotoxicity	en_US
dc.title	New 1,3,4-Oxadiazole based Schiff base Derivatives: Synthesis, Characterization and Antibacterial Activity Along With in Silico Studies	en_US
dc.type	Article	en_US