Abstract:
As a formulation, tablets are made with plant extracts, such as vasaka powder and the
extracts of Carica papaya and Embelica officinalis. The process of dry granulation
was used to create these pills. In this article, herbal pills were made using an extract
of the fruits of Embelica officinalis and the leaves of Carica papaya. Cold extraction
and maceration techniques were used to get extracts from Carica papaya leaves, while
the maceration process was used to extract fruit from Embelica officinalis. After
drying, the three extracts were combined. To create granules, these extracts were
subsequently impregnated with various excipients, including lubricants, super
disintegrating agents, binding agents, and diluents. Then, these granules were
assessed using a variety of factors, including Hausner's Ratio, void volume, Carr's
Index, tapped density, bulk density, and angle of repose. After that, the machine was
used to punch these grains into the appropriate size and form for tablets. The physical
appearance, weight variation, friability, disintegration time, hardness test, and
thickness of the tablets were investigated after they were prepared. Additionally, the
taste and sweetness of the tablets are taken into consideration when determining their
acceptance. Recent research has demonstrated the potential benefits of papaya leaf
herbal extract as an anti-inflammatory, anti-tumor, immunomodulatory, and woundhealing
agent, including as an antioxidant. The fresh pulp of amla fruit contains 400–
550 mg of ascorbic acid, which is a good natural source of vitamin C. It is also
abundant in minerals, including calcium, iron, and phosphorus. Amla is utilized as an
immunomodulatory drug, which boosts the patient's immunity. The study's objective
is to design, develop, and optimize a dengue dosage form. It is predicated on the
mingling of chemical and synthetic chemicals with natural plant substances to create
an efficient unit dosage form that will improve patient compliance. Vasaka possesses
anti-inflammatory properties. Adhatoda Vasica possesses antimicrobial and
antibacterial properties. it is useful for treating dengue.
