Formulation and evaluation of vitiligo herbal gel

Abstract

Features of vitiligo are Reduction in number of melanocytes in the epidermis and mucous membranes, a chronic multifactorial condition impacted by oxidative stress, toxins, and heredity. The pathophysiology of this old religious literature is now more understood. This paper examines surgical, herbal, and Ayurvedic treatments for vitiligo, with a focus on Psoralea corylifolia because of its long history of usage and many health advantages. Examining its 163 chemical constituents, which possess anti-inflammatory, antibacterial, and antioxidant characteristics, indicates possible treatment paths. Targets for drug development include regulatory T cells, interleukin-17, tumor necrosis factor-alpha, and keratinocyte modulators. The study recommends investigating new herbal remedies for the treatment of vitiligo.