• Solubility Enhancement Of Poorly Soluble Drugs By Formulation Of Solid Dispersion Using Soluplus® As A Carrier 

  Sheikh, Mohammed Farhan M.; Ughreja, Reena (2024-07-16)

  Treatment of tuberculosis makes great use of rifampicin. While Abiraterone Acetate is generally used for the treatment of prostate cancer, Duloxetine Hydrochloride is advised for the treatment of major depressive disorder. ...
• Formulation And Development Of Solid Self Emulsifying Drug Delivery Systems Of Antihypertensive Drugs 

  Buddhadev, Sheetal Sandip; Dr. Kevinkumar, C. Garala (2024-04-03)

  Benidipine (BD), a dihydropyridine calcium channel blocker indicated in hypertension angina therapy, presents challenges with oral bioavailability owing to hepatic first-pass metabolism and high lipophilicity (log P of ...
• Spectroscopic and Chromatographic Method Development and Validation for the estimation of Antimicrobial Agents and their combinations in Synthetic Mixture and Assay Method for the Pharmaceutical Dosage Forms 

  Pandya, Yogi Umeshbhai; Dr. Samixa, R. Patel (2022-10-08)

  Background: The present research work comprises of the Stability Indicating RP-HPLC newlineanalytical method development and validation for selected drugs andamp; pharmaceutical dosage newlineforms belonging to the ...
• Determination of ETORICOXIB in Bulk Formulations by RP-HPLC methods 

  Bansal, Aayushi (World Journal of Pharmaceutical Research, 2022)

  For the determination of Etoricoxib in bulk formulations a rapid, selective and simple RP-HPLC method was formed and used, by optimizing stationary phase, composition of mobile phase and other parameters. Study was ...
• Influence of eutectic mixture as a multi-component system in the improvement of physicomechanical and pharmacokinetic properties of diacerein 

  Patel, Rajeshri; Raval, Mihir; Pethani, Trupesh; Sheth, Navin (Advanced powder Technology, Elsevier, 2020)

  A multi-component system of diacerein (DIA) with 2, 4 – dihydroxybenzoic acid (DHA) as coformer at various molar compositions was formulated to simultaneously improve solubility, compressibility and bioavailability of ...
• Functionality improvement of Nimesulide by eutectic formation with nicotinamide: Exploration using temperature-composition phase diagram 

  Patel, Rajeshri; Raval, Mihir; Bagathariya, Ajrudeen; Sheth, Navin (Advanced powder Technology, Elsevier, 2019)

  The aim of present work was to explore the temperature-composition phase diagram for detection of for mation of a multi-component system. Fusion of model drug Nimesulide (NIM) and Nicotinamide (NIC) was prepared and ...
• Differential scanning calorimetry: A screening tool for the development of diacerein eutectics 

  Patel, Rajeshri; Raval, Mihir (Resuls in Chemestry, Elsevier, 2022)

  The application of DSC technique has been employed for better understanding the behavior of multi-component solid forms of poorly water-soluble drugs. Therefore, the purpose of the present work was to investigate the ...
• Pharmacognostic Parameters of Eucalyptus globulus Leaves 

  Shah, Gagan; Kaur, Maninderjit; Singh, prabh; Rahar, Sandeep; Dhabliya, Falgun; Arya, Yuvraj; Shri, Richa (Pharmacognosy Journal, 2012)

  Eucalyptus globulus Labill synonym blue gum tree (Family: Myrtaceae) is an evergreen tree, one of the most widely cultivated trees native to Australia, South Africa, India and Southern Europe. The bark was used against ...
• Estimation of boswellic acid in S. compound capsule 

  Rachh, Punit; Rachh, Milan; Zala, Vishal; Pinak, Sanchania; Lakkad, Arvind; Patel, Dharmesh; Dhabaliya, Falgun; Dharamsi, Abhay (International Journal of Pharmaceutical Science, 2012)

  S. compound capsule is a proprietary herbal market formulation claimed to be used for treatment of osteoarthritis. It contains Sallaki (Boswellia Serrata). Today there are requirements for modern routine quality control ...
• RP-HPLC stability method development & validation for anti-HIV drugs cabotegravir & rilpivirine in I.M. injection and in human plasma 

  Pandya, Yogi; Patel, Samixa (International Journal of Health Sciences, 2022)

  In Pharmaceutical & Medical Health Sciences there are necessities for development of analysis methods for medicines in various dosage forms. Currently the use of RP-HPLC is primarily applied for testing of medicines ...
• A novel rapid combined RP-HPLC stability method development and validation for antiviral HIV combinations lamivudine, tenofovir, doravirine in dosage form and its application to in vitro dissolution 

  Pandya, Yogi; Patel, Samixa (International Journal of Health Sciences, 2022)

  In the analysis of the pharmaceutical agents new sophisticated chromatographic methods have been utilized for the quality control purpose. In the current scenario ample amount of new drugs and newer pharmaceutical ...
• Development and validation of zero absorbance method for simultaneous estimation of aliskiren and amlodipine in combined dosage form 

  Patel, Samixa; Patel, Chhaganbhai (Asian Pharma Press, 2016)

  A simple, accurate, precise, economical and reproducible method was developed for simultaneous estimation of aliskiren and amlodipine in Combined Pharmaceutical Dosage Forms. The excipients in the commercial tablet preparation ...
• Development and Validation of Spectrophotometric Method for Determination of Aliskiren, Amlodipine and Hydrochlorothiazide in combined Pharmaceutical Dosage Forms 

  Patel, Samixa; Patel, Chhaganbhai (Asian Pharma Press, 2014)

  A simple, accurate, precise, economical and reproducible method was developed for simultaneous estimation of aliskiren, amlodipine and hydrochlorothiazide in Combined Pharmaceutical Dosage Forms. The excipients in the ...
• Amlodipine: A Review of Analytical Methods 

  Patel, Samixa; Patel, Chhaganbhai (Inventi Journals, 2012-05)

  Amlodipine is a long-acting calcium channel blocker (dihydropyridine (DHP) class) used as an anti-hypertensive and in the treatment of angina. Like other calcium channel blockers, amlodipine acts by relaxing the smooth ...
• Development and validation of spectrophotometric method for determination of Olmesartan, amlodipine and hydrochlorothiazide in combined pharmaceutical dosage forms 

  Patel, Samixa; Patel, Chhaganbhai (Novel Science International Journal of Pharmaceutical Science, 2012)

  A simple, accurate, precise, economical and reproducible method was developed for simultaneous estimation of olmesartan, amlodipine and hydrochlorothiazide in Combined Pharmaceutical Dosage Forms. The excipients in the ...
• Simultaneous Determination of Nebivolol and Amlodipine in Combined Dosage Form by Derivative Spectrophotometry 

  Patel, Samixa; Patel, Shweta; Patel, Jignesh; Patel, Paresh (Research J. Pharm. and Tech., 2011-01)

  Simple and accurate method to determine Nebivolol and Amlodipine, in tablet dosage form, was developed and validated using Derivative Spectrophotometry. Derivative spectrophotometric method was based on the determination of ...
• Development and Validation of High-Performance Thin-Layer Chromatography Method for Determination of Nebivolol and Amlodipine besylate in Combined Dosage Forms 

  Patel, Samixa; Patel, Shweta; Patel, Jignesh; Patel, Paresh (Journal of Pharmacy Research, 2010-01)

  The manuscript describes validated High-Performance Thin-Layer Chromatography (HPTLC) method for the estimation of Nebivolol (NEB) and Amlodipine (AML) in combined dosage form. The HPTLC separation was achieved on an ...
• Synthesis and Evaluation of Some Novel Substituted 1, 3, 4- Oxadiazole and Pyrazole Derivatives for Antifungal Activity 

  Rabara, Parag; Jivani, Nurudin; Pattan, Shashikant; Garala, Kevin (Inventi Journals, 2016)

  A series of 1,3,4-oxadiazole and pyrazole derivatives have been synthesized and evaluated for antifungal activity. The structures of synthesized compounds were confirmed by IR, 1H NMR, Mass and CHN analysis. These compounds ...
• Formulation and Characterization of Taste Masked Mouth Dissolving Tablets of Tramadol HCl Using Different Approaches 

  Garala, Kevin; Patel, Anjali; Rabara, Parag (Inventi Journals, 2016)

  To overcome difficulty in swallowing tablets or capsules, scientists have considerably dedicated their effort to develop novel drug delivery systems which enhance safety and efficacy of drug molecule and to achieve ...
• Formulation and Development of W/O Type Microemulsion based Transdermal Systems for Verapamil Hydrochloride 

  Dhingani, Anjali; Patel, Jaydeep; Garala, Kevin; Patel, Hardik; Dharamsi, Abhay (Inventi Journals, 2013)

  The aim of the present investigation was to design and develop a novel microemulsion (ME) based transdermal drug delivery system of highly water soluble drug, verapamil HCl (VPLH) to enhance its therapeutic efficacy. ...

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