Clindamycin is a potent lincosamide antibiotic against susceptible anaerobic bacteria and gram-positive aerobes. Furthermore, CLN also has anti-inflammatory activities. It is applied topically in the management of acne ...

A POCl 3 catalyzed, efficient, one-step and solvent-free synthesis of novel thieno[2,3-d] pyrimidin-4(3H)-one derivatives from 2-amino-4,5-substitutedthiophene-3-carbonitrile has beendeveloped under conventional heating ...

Background: Mycobacterium tuberculosis causes tuberculosis (TB), the most lethal infectious disease in the world that affects people of all ages. The aim of our study was to estimate the prevalence of TB in the Gujarat state ...

Mebendazole (MBZ) has been proven as a repurposing molecule against colorectal cancer. Unfortunately, its clinical application isconstrained by its extremely poor solubility and bioavailability. The aim of the current work ...

Itraconazole (ITZ) is an antifungal triazole, used to treat systemic and superficial fungal infections. Its clinical effectiveness is limited due to its low water solubility which results in poor bioavailability. Therefore, ...