Benidipine (BD), a dihydropyridine calcium channel blocker indicated in hypertension angina therapy, presents challenges with oral bioavailability owing to hepatic first-pass metabolism and high lipophilicity (log P of ...

For the determination of Etoricoxib in bulk formulations a rapid, selective and simple RP-HPLC method was formed and used, by optimizing stationary phase, composition of mobile phase and other parameters. Study was ...

The aim of present work was to explore the temperature-composition phase diagram for detection of for mation of a multi-component system. Fusion of model drug Nimesulide (NIM) and Nicotinamide (NIC) was prepared and ...

Eucalyptus globulus Labill synonym blue gum tree (Family: Myrtaceae) is an evergreen tree, one of the most widely cultivated trees native to Australia, South Africa, India and Southern Europe. The bark was used against ...

In Pharmaceutical & Medical Health Sciences there are necessities for development of analysis methods for medicines in various dosage forms. Currently the use of RP-HPLC is primarily applied for testing of medicines ...

A simple, accurate, precise, economical and reproducible method was developed for simultaneous estimation of aliskiren and amlodipine in Combined Pharmaceutical Dosage Forms. The excipients in the commercial tablet preparation ...

Amlodipine is a long-acting calcium channel blocker (dihydropyridine (DHP) class) used as an anti-hypertensive and in the treatment of angina. Like other calcium channel blockers, amlodipine acts by relaxing the smooth ...

Simple and accurate method to determine Nebivolol and Amlodipine, in tablet dosage form, was developed and validated using Derivative Spectrophotometry. Derivative spectrophotometric method was based on the determination of ...

A series of 1,3,4-oxadiazole and pyrazole derivatives have been synthesized and evaluated for antifungal activity. The structures of synthesized compounds were confirmed by IR, 1H NMR, Mass and CHN analysis. These compounds ...

The aim of the present investigation was to design and develop a novel microemulsion (ME) based transdermal drug delivery system of highly water soluble drug, verapamil HCl (VPLH) to enhance its therapeutic efficacy. ...