03.Faculty of Health Sciences: Recent submissions

  • A Review on Solid Self Emulsifying Drug Delivery Systems and Dosage Forms 
    Dholakiya, Arpana; Shah, Akash; Jakasania, Pratik; Patel, Jaydeep; Garala, Kevin (Inventi Journals, 2013)
    Combinatorial chemistry and high-throughput screening used in drug discovery have resulted in a 70% of new drug candidates shown poor aqueous solubility in recent years which leads to low oral bioavailability. In clinical ...
  • Formulation and Development of Microemulsion Based Gel (Mbg) of Ibuprofen for Topical Drug Delivery 
    Shah, Akash; Vyas, Kalyani; Aviya, Ketan; Jivani, Pankti; Dobariya, Vishal; Patel, Jaydeep; Garala, Kevin (Inventi Journals, 2013)
    The aim of the present study was to formulate an Ibuprofen loaded microemulsion based gel (MBG) for the topical delivery. The oil phase selected for the preparation of stable microemulsion was IsoPropyl Myristate (IPM). ...
  • Development and Validation of RP-HPLC Method for Simulataneous Estimation of Lercanidipine HCl and Atenolol in Pharmaceutical Formulations 
    Dhingani, A.; Patel, J.; Garala, K.; Dharamsi, A. (Inventi Journals, 2012)
    A simple, precise and RP-HPLC (reverse phase – high performance liquid chromatographic) method was developed and validated for the simultaneous determination of lercanidipine HCl (LDPH) and atenolol (AT) in pharmaceutical ...
  • Overcoming Limitations in Dissolution Testing of Poorly Water Soluble Racecadotril 
    Garala, K.; Patel, J.; Dhingani, A.; Raval, M.; Dharamsi, A. (Inventi Journals, 2012)
    The conventional dissolution test, particularly the USP apparatus I and II, remains an important tool in the field of the pharmaceutical product development. For accurate dissolution characterization, sink conditions, ...
  • Development and Validation of A Rapid and Sensitive HPLC Method for Estimation of Racecadotril 
    G., Kevin; Patel, J.; Dhingani, A.; Raval, M.; Dharamsi, A. (Inventi Journals, 2012)
    : A simple, specific, sensitive and rapid reverse phase high performance liquid chromatographic (HPLC) method for the determination of racecadotril (RCD) was developed and validated. Sample preparation involved simple ...
  • Design and Evaluation of Transdermal Drug Delivery System of Nebivolol Hydrochloride 
    Garala, K.; Kapadiya, M.; Patel, J.; Patel, A.; Raval, M.; Dharamsi, A. (Inventi Journals, 2013)
    Nebivolol hydrochloride is a selective β1-receptor antagonist with antihypertensive properties having plasma half life of 10 h and 12 % oral bioavailability. In the present work transdermal matrix patches of Nebivolol ...
  • Solubility Enhancement of Candesartan by Polyamidoamine Dendrimers 
    Patel, Jaydeep; Garala, Kevin; Dhingani, Anjali; Raval, Mihir; Dharamsi, Abhay (Inventi Journals, 2012)
    The present study was aimed for solubility enhancement of candesartan (CND) by dendrimers. The aqueous solubility of CND was measured in the presence of dendrimers in distilled water. The effect of variables (pH condition, ...
  • An Emerging Trend in Oral Drug Delivery Technology : Rapid Disintegrating Tablets 
    Mehta, Kuldeep; Garala, Kevin; Basu, Biswajit; Bhalodia, Ravi; Joshi, Bhavik; Charyulu, R. Narayana (Journal of Pharmaceutical Science and Technology, 2010)
    Recent advances in novel drug delivery system aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach ...
  • Physical Penetration Enhancement Through TDDS: A Review 
    Garala, Kevin; Basu, Biswajit; Dharamsi, Abhay (Journal of Pharmacy Research, 2010)
    The delivery of drugs into systemic circulation via skin has generated lot of interest in recent time. Transdermal drug delivery is now a promising route of drug delivery system. The transdermal drug delivery system has ...
  • Lycopene: A novel anti-oxidant and anticancer agent 
    Basu, Biswajit; Garala, Kevin; Dharamsi, Abhay (Journal of Pharmacy Research, 2010)
    Prostate cancer is a major public health problem in nations that have an affluent culture with an aging population. Over the last decade the development of chemopreowering the risk of prostate cancer. Lycopene is the most ...
  • Formulation and Evaluation of Pimozide Buccal Mucoadhesive Patches 
    Basu, Biswajit; Garala, Kevin; Thimmasetty, J. (International Journal of Pharmaceutical Sciences and Nanotechnology, 2010-03)
    Within the oral mucosal cavity, the buccal region offers an attractive route of administration for systemic drug delivery. Pimozide patches were prepared using HPMC (15 & 47 cPs), carbopol 934, poly vinyl alcohol, and ...
  • Solid lipid nanoparticles :A promising tool for drug delivery system 
    Basu, Biswajit; Garala, Kevin; Bhalodia, Ravi; Joshi, Bhavik; Mehta, Kuldeep (Journal of Pharmacy Research, 2010)
    Solid lipid nanoparticles (SLNs) technology represents a promising new approach to lipophilic drug delivery. Solid lipid nanoparticles are important advancement in this area. The biodegradable and bioacceptable nature of ...
  • Formulation and In Vitro Evaluation of Periodontal Films Containing Metronidazole 
    Basu, Biswajit; Garala, Kevin; Tyagi, Manojkumar; Prabhushankar, G.; Sathesh Babu, P. (Research Journal of Pharmaceutical Dosage Forms and Technology., 2009)
    Local delivery devices are designed to deliver the drug locally into periodontal pocket. Metronidazole is a nitroimidazole used to treat protozoal infections. For local delivery, metronidazole films were prepared by ...
  • Alternative to drug delivery system: Chromotherapy 
    Garala, Kevin; Basu, Biswajit; Bhalodia, Ravi; Mehta, Kuldeep; Joshi, Bhavik (Drug Invention Today, 2009-07)
    Chromotherapy, also called Color Therapy, Colorology or Light Therapy, is an alternative medicine method for healing. Color is use to balance energy wherever our bodies are lacking, be it physical, emotional, spiritual, ...
  • Chemical Penetration Enhancement: A Review 
    Garala, Kevin; Faldu, Nidhi; Basu, Biswajit; Bhalodia, Ravi; Mehta, Kuldeep; Joshi, Bhavik (Journal of Pharmacy Research, 2009-08)
    Transdermal drug delivery system is now a promising drug delivery system. Modern transdermal drug delivery systems are products of basic pharmaceutical research that took place during the last third of the 20th century. ...
  • Formulation Development of Tramadol Hydrochloride Rapid-disintegrating Tablets Using Simplex Lattice Design 
    Ekshinge, Vinit; Garala, Kevin (Research Journal of Pharmacy and Technology (RJPT), 2009-12)
    The effect of a mixture of super disintegrants on the disintegration time and in vitro drug release rate was studied. In this study, an attempt had been made to prepare rapid disintegrating tablets of the drug using ...
  • Development of the UV spectrophotometric method of Olmesartan medoxomil in bulk drug and pharmaceutical formulation and stress degradation studies 
    Patel, Jaydeep; Garala, Kevin; Patel, Anjali; Raval, Mihir; Sheth, Navin (Medknow Publications, 2011-03)
    A simple, sensitive, specific, spectrophotometric method was developed for the detection of Olmesartan medoxomil (OLM) in bulk and pharmaceutical formulations. The optimum conditions for the analysis of the drug were ...
  • Formulation and in-vitro characterization of monolithic matrix Transdermal systems using hpmc/eudragit s 100 polymer blends 
    Garala, Kevin; Shinde, Anil; Shah, Pratik (International Journal of Pharmacy and Pharmaceutical Sciences, 2009-12)
    In the present work, monolithic matrix transdermal systems containing tramadol HCl were prepared using various ratios of the polymer blends of hydroxy propyl methyl cellulose (HPMC) and Eudragit S 100 (ES) with triethyl ...
  • Solubility of aceclofenac in polyamidoamine dendrimer solutions 
    Patel, Jaydeep; Garala, Kevin; Basu, Biswajit; Raval, Mihir; Dharamsi, Abhay (International Journal of Pharmaceutical Investigation, 2011-07)
    In the present study we investigated the effect of polyamidoamine (PAMAM) dendrimers on the aqueous solubility of aceclofenac. The aqueous solubility of aceclofenac was measured in the presence of dendrimers in distilled ...
  • Influence of excipients and processing conditions on the development of agglomerates of racecadotril by crystallo‑co‑agglomeration 
    Garala, Kevin; Patel, Jaydeep; Patel, Anjali; Raval, Mihir; Dharamsi, Abhay (International Journal of Pharmaceutical Investigation, 2012-12)
    Purpose: The purpose of the present investigation was to improve the flow and mechanical properties of racecadotril by a crystallo‑co‑agglomeration (CCA) technique. Direct tableting is a requirement of pharmaceutical ...

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