02. Department of Chemistry: Recent submissions

Now showing items 101-120 of 156

Synthesis and Characterization of Liquid Crystalline Property of a New Thermotropic Liquid rystalline Molecules with Terminal End Group and DSC Study

Baku, Neha K.; Travadi, Jwalant. J.; Ladva, Kartik D. (International Journal of Research in Engineering and Science, 2023)

We synthesized and studied a novel homologous series of esters with a lateral methoxy group and a terminal nheptyl benzoate group to study how mesomorphic behavior correlates with structure. The twelve-membered series ...
Effect of Laterally Substituted Methoxy Group on the Liquid Crystalline Behavior of Novel Ester Molecules

Baku, Neha K.; Travadi, Jwalant. J.; Ladva, Kartik D. (Bentham Science Publishers / Current Physical Chemistry, 2024)

Background: The aim of this research is to study the effect of length-to-width ratio on mesomorphism to enhance the understanding of its potential applications. This will be achieved by synthesizing a unique and innovative ...
Synthesis and Study of Mesomorphic Properties of Liquid Crystalline Compounds Involving Lateral -OCH3 Group and Vinyl Carboxylate Central Linkage

Makavana, Gaurang P.; Baku, Neha K.; Travadi, Jwalant J. (World Scientific News, 2024)

In the present investigation, a newly synthesized ester homologous series of mesogenic compounds having a vinyl carboxylate group as central linkage with two phenyl rings and a laterally substituted methoxy group as well ...
2-Chloroquinolinyl-thiazolidine-2,4-dione Hybrids as Potential α-Amylase Inhibitors: Synthesis, Biological Evaluations, and In Silico Studies

Karmur, S. B.; Dholariya, M. P; Patel, A. S; Karmur, M. B; Maliwal, D; Pissurlenkar, R. R; Kapuriya, N. P. (2024)

Recently, molecular hybridization strategy has paved a way to develop novel lead compounds for the α‐amylase targeted antidiabetic therapy. In this study, we disclosed a series of new hybrids of thiazolidine‐2,4‐diones ...
Synthesis, anti-microbial evaluation, and in silico studies of novel quinoline-isoxazole hybrids

Mandir, Deep P.; Mandir, Shivani D.; Kamdar, Jignesh H.; Tala, Satishkumar D. (Taylor & Francis / Synthetic Communications, 2024)

A series of novel quinoline-isoxazole hybrids 6a–o has been synthe-sized via multistep synthetic approach involving hetero Diels-alder reaction strategy. The target compounds were obtained in good yield, using low-cost ...
Indole–thiazolidinedione–triazole hybrids: synthesis, molecular docking, absorption, distribution, metabolism and excretion (ADME) profiling, and biological evaluation …

Dholariya, M. P.; Patel, A. S. (Chemistry Letters, 2024)

A novel series of hybrid indole–thiazolidinedione–triazole derivatives (6a-l) were synthesized and assessed for their in vitro inhibitory activity against porcine pancreatic α-amylase. The synthetic procedure consists of ...
Steroid and fatty acid contents from the leaves of Carica papaya

Devmurari, Vishvraj V.; Patel, Poojaben P.; Jadeja, Rajeshreeba A.; Bhadaniya, Cameykumari P.; Aghara, Priti P.; Patel, Anilkumar S.; Tala, Satishkumar D.; Savant, Mahesh M.; Ladva, Kartik D.; Nariya, Pankajkumar B. (Folia Medica, 2021)

Aim: To extract and identify the non-polar entities from the leaves of Carica papaya, a plant used for medicinal purpose as folk medicine. Materials and methods: Petroleum ether extract of the Carica papaya leaves was used ...
Triethanolamine‐catalyzed expeditious and greener synthesis of 2‐amino‐4H‐chromenes

Patel, Anilkumar S.; Tala, Satishkumar D.; Nariya, Pankajkumar B.; Ladva, Kartik D.; Kapuriya, Naval P. (Wiley/ Journal of the Chinese Chemical Society, 2019)

Triethanolamine (TEOA), an inexpensive and eco-friendly base, was used to efficiently catalyze the three-component condensation reaction of heterocyclic/aromatic aldehyde, (α/β)-naphthol, and malononitrile in water to give ...
Exploration of graphitic carbon from crude oil vacuum residue

Dalsania, Ravi; Gajera, Hasmukh; Savant, Mahesh M. (Elsevier/ Carbon Trends, 2024)

Preparation of graphitic carbon from low value refinery waste has captivated immense interest in past years owing to its low cost and abundant nature. Successful utilization of petroleum vacuum residue is a major challenge ...
Synthesis, In Vitro Antimalarial Evaluation, ADMET Properties, and Molecular Docking Studies of Novel Thiazolo [3, 2-a] pyrimidine Derivatives

Jatiya, J. N.; Patel, A. S.; Savant, Mahesh M. (Pleiades Publishing, Ltd. / Russian Journal of General Chemistry, 2024)

A series of novel (Z)-N′-(1-(aryl)ethylidene)-6-cyano-5-imino-3-methyl-7-(methylthio)-5H-thiazolo[3,2-a]pyrimidine-2-carbohydrazide derivatives was synthesized. All the synthesized compounds were investigated for antimalarial ...
Synthesis, In Vitro Antimicrobial Evaluation, ADMET Properties, and Molecular Docking Studies of Novel Thiazole Derivatives

Jatiya, J. N.; Patel, A. S.; Savant, Mahesh M. (Pleiades Publishing Ltd. / Russian Journal of General Chemistry, 2023)

A series of novel ethyl (Z)-2-cyano-3-[(4-methyl-5-{2-[(Z)-1-arylethylidene]hydrazine-1-carbonyl}-thiazol-2-yl)amino]-3-(methylthio)acrylate derivatives was synthesized through four step method. The process generates novel ...
Synthesis, antidiabetic aSynthesis, antidiabetic activity and in silico studies of benzo[b]thiophene based small molecule α-amylase inhibitors

Joshi, Rupal J.; Dholariya, PMonil; Savankumar, R; Chothani, a (Journal of Molecular Structure, 2024)

Benzo[b]thiophene has been implicated as molecular framework in the drug discovery against broad spectrum of biological targets. In the antidiabetic drug regime, benzo[b]thiophene based SGLT2 and ALR2 inhibitors have been ...
Synthesis, In Vitro Antimalarial Evaluation, ADMET Properties, and Molecular Docking Studies of Novel Thiazolo[3,2-a]pyrimidine Derivatives

Patel, A. S.; Jatiyaa, J. N.; Savant, M. M. (Russian Journal of General Chemistry, 2024)

A series of novel (Z)-N′-(1-(aryl)ethylidene)-6-cyano-5-imino-3-methyl-7-(methylthio)-5Hthiazolo[3,2-a]pyrimidine-2-carbohydrazide derivatives was synthesized. All the synthesized compounds were investigated for antimalarial ...
Synthesis, type II diabetes inhibitory activity and docking studies of novel thiazole molecules

Jadeja, Jaysinh I.; Savant, Mahesh M. (Indian Academy of Sciences/ Journal of Chemical Sciences, 2023)

A series of novel ethyl (E)-2-cyano-3-((4-methyl-5-(arylcarbamoyl)thiazol-2-yl)amino)-3-(methylthio)acrylate have been synthesized starting from various 2-amino-N-aryl-4-methylthiazole-5-car-boxamide. The reaction of ...
Design and Synthesis of Some Novel Thiazole Molecules

Jadeja, Jaysinh I.; Savant, Mahesh M. (International Journal of Pharmaceutical Sciences and Research, 2023)

A series of novel (Z)-3-((5-(2-((E)-arylidene) hydrazine-1- carbonyl)-4-methylthiazol-2-yl)amino)-2-cyano-3-(methylthio) acrylate 4a-t molecules have been synthesized and characterized by 1H NMR, 13C NMRand mass spectral ...
Synthesis of thiazolo [3, 2-a] pyrimidine molecules, in vitro cytotoxic evaluation and molecular docking studies

Jadeja, Jaysinh; Savant, Mahesh (Journal of the Iranian Chemical Society, 2023-03-04)

Novel hybrid molecules of thiazolopyrimidine 4a–j have been prepared starting from various thiazoles 3a–j. The reaction of thiazoles 3a–j with thiourea yielded hybrid molecules 4a–j in an excellent yield. These molecules ...
High‑performance thin‑layer chromatography‒spectrodensitometric determination of diltiazem hydrochloride and its commonly occurring degradation impurity

Varu, H. L; Nariya, P. B; Patel, A. S; Gadher, M; Makhasana, M.; Lunagariya, K.; Ambasana, M. A. (Journal of Planar Chromatography, 2024)

The present work encompassed the assay quantification of diltiazem hydrochloride and its degradation impurity F by high-performance thin-layer chromatography (HPTLC). HPTLC was performed with chloroform‒methanol‒formic ...
An efficient synthesis of novel isoxazole bearing pyrazole derivatives via [3+ 2] heteroannulation using cupric acetate

Audichya, Vipul B.; Savant, Mahesh M.; Naliapara, Yogesh T. (Wiley/ Journal of Heterocyclic Chemistry, 2022)

The synthesis of novel 3-(4,5-dichloro-2-fluorophenyl)-1-phenyl-4-(3-phenylisoxazol-5-yl)-1H-pyrazole(7a–p) has been achieved via [3 + 2] heteroannulation reaction 3-(3-[4,5-dichloro-2-fluorophenyl]-1-phenyl-1H-pyrazol-4 ...
Synthesis, anticancer evaluation and in silico studies of novel N-substituted arylidenethiazolidine-2,4-dione derivatives as adenosine monophosphate-activated protein kinase activators

Chothani, S. R.; Chamakiya, C. A.; Joshi, R. J.; Karmur, M. B.; Karmur, S. B.; Varu, H. L.; Kapuriya, N. P. (Journal of Heterocyclic Chemistry, 2024)

Design and development of AMP‐activated protein kinase (AMPK) activator emerged as a potential therapeutic approach for various types of cancers. In this context, thiazolidine 2,4‐dione was invariably found as an important ...
Synthesis, Spectroscopic and In-Vitro Antimicrobial Screening of Some Novel Transition Metal Based Heterochelates

Gajera, Prashant; Vadodaria, Milan; Raja, Maulik; Cholera, Archana (IJBPAS, 2023-12-01)

New Mn(II), Cu(II) and Zn(II) heterochelates were synthesize by reacting Semicarbazone, Thiosemicarbazone and Antipyrine with 2 amino 3,5 dibromo benzaldehyde. All the synthesized Schiff’s base ligands and their heterochelates ...

Now showing items 101-120 of 156

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