• Anti-proliferative activity of surfactins on human cancer cells and their potential use in therapeutics 

  Tank, Jigna G.; Pandya, Rohan V. (Peptides, 2022)

  Surfactins are cyclic lipopeptides that are isolated from various Bacillus strains. They are made up of heptapeptides and β-hydroxy fatty acids of variable chain lengths of carbon atoms. Therapeutically they are known to ...
• A Solvent-tolerant Alkaline Lipase from Bacillus sp. DM9K3 and Its Potential Applications in Esterification and Polymer Degradation 

  Singh, P.; Patel, V.; Shah, V.; Madamwar, D. (Applied Biochemistry And Microbiology, 2019-12)

  Solvent-tolerant lipase produced by Bacillus sp. DM9K3 has been isolated from the hypersaline area, White Rann of Kachchh, Gujarat, India. The strain initially showed lipase activity of 11.1 U/mL in a basal medium which ...
• White Rann of Kachchh harbours distinct microbial diversity reflecting its unique biogeography 

  Singh, Prachi; Jain, Kunal R.; Shah, Varun; Madamwar, Datta (Science Of The Total Environment, 2021-08)

  The understanding of sub-surface soil microbial diversity is limited at both saline and hypersaline ecosystems, even though salinity is found to affect the microbial community in aqueous and terrestrial environment. In ...
• Melanin and its Precursors as Effective Antiviral Compounds: 

  Kurian, Noble K (Molecular Biology: Open Access, 2021)

  Melanins are ubiquitous pigment which plays a diverse role in organisms ranging from bacteria to human beings. Its unique properties made it an important compound for study in diverse fields from electronics to drug ...
• Mechanisms of group B Streptococcus-mediated preterm birth: lessons learnt from animal models 

  Kurian, Noble K; Modi, Deepak (Reproduction and Fertility, 2022-07)

  Group B Streptococcus (GBS) is an opportunistic pathogenic bacterium which upon colonization in the female reproductive tract can cause preterm births, fetal injury, and demise. Several determinants for GBS pathogenesis ...
• Marine Microorganisms as Potential Source of Quorum-Sensing Inhibitory Compounds 

  kachhadiya, Dimple; Ojha, Yashika (International Research Journal on Advanced Engineering and Management, 2024)

  Antibiotics are extensively utilized globally, and the rate of antibiotic resistance is increasing more rapidly than ever. Since the introduction of antibiotics, the overuse of antibiotics caused selection pressure, and ...
• Comparative Analysis of Artificial Neural Network and Long Short-term Memory Techniques for Predicting Air Quality in Smart Cities: Ahmadabad City 

  Varia, D.J.; Kothari, A.M. (Indian Journal of Environmental Protection, 2022-04)

  Over the last few decades, air quality has turned into a critical environmental issue which has made more prominent effect on human health. Because air quality greatly affects the everyday existence of human, it is essential ...
• A New Perspective on Metabolites and Bioactive Compounds from Fungi 

  Bas, Abhishikta; Choi, Seo-Ree; Nathan, Vinod Kumar; Balasubramaniyam, Thananjeyan (American Journal Of Chinese Medicine, 2023)

  Fungi play an important role in the solution to important global problems. Making use of processes and goods that are based on fungi can help promote sustainability by making the most efficient use of natural resources. ...
• Design, synthesis, MTT assay, DNA interaction studies of platinum(II) complexes 

  Lunagariya, Miral V; Thakor, Khyati P; Waghela, Bhargav N; Vaidya, Foram U; Patel, Chadramani Pathak & Mohan N (2016-12-07)

  The square planar Pt(II) complexes of the type [Pt(Ln)(Cl2)] (where Ln = L1-3 = thiophene-2- carboxamide derivatives and L4-6 = thiophene-2-carbothioamide derivatives) have been synthesized and characterized by physicochemical ...
• Design, synthesis, pharmacological evaluation and DNA interaction studies of binuclear Pt(II) complexes with pyrazolo[1,5‐a]pyrimidine scaffold 

  Lunagariya, Miral V; Thakor, Khyati P; Waghela, Bhargav N; Pathak, Chadramani (2017-11-09)

  Substituted pyrazolo[1,5‐a]pyrimidine ligands were synthesized by cyclization, using 3‐(thiophen‐2‐yl)‐1H‐pyrazol‐5‐amine with substituted enones (3‐phenyl‐ 1‐(pyridin‐2‐yl)prop‐2‐en‐1‐one) in presence ofKOHandDMFas solvent ...
• Synthesis, characterization and biological application of 5-quinoline 1,3,5-trisubstituted pyrazole based platinumIJII) complexes† 

  Lunagariya, Miral V; Thakor, Khyati P; Varma, Reena R; Bhargav N, Waghela,; Chandramani Pathak and Mohan N, Patel (2017-12-11)

  Square planar mononuclear platinumIJII) complexes were synthesized in the presence of neutral bidentate heterocyclic (5-quinoline 1,3,5-tri-substituted pyrazole scaffold) ligands and K2PtCl4 salt. The synthesized compounds ...
• Silibinin, A Natural Blend In Polytherapy Formulation For Targeting Cd44v6 Expressing Colon Cancer Stem Cells 

  Patel, Shanaya; Waghela, Bhargav; Shah, Kanisha; Vaidya, Foram; Mirza, Sheefa; Rawa, Rakesh (2018-11-19)

  Colon cancer stem cells have been attributed to poor prognosis, therapeutic resistance and aggressive nature of the malignancy. Recent reports associated CD44v6 expression with relapse, metastasis and reduced 5-year ...
• Leishmania donovani adenylate kinase 2a prevents ATP-mediated cell cytolysis in macrophages 

  Shah, Kulkarni P.G; Waghela, B.N; Pathak, C.M; Pappachan, A (2019-05-16)

  In Leishmania spp. ATP utilizing enzymes serves as a key role in preserving integrity of host cells for survival of parasite. Earlier reports suggested that Adenylate kinase (AK) a phosphotransferase enzyme released ...
• Evaluation of antimitotic activity of herbal extracts using plant‑based model systems and their cytotoxic potential against human colon carcinoma cells 

  Parmar, Mayur P; Waghela, Bhargav N; Vaidya, Foram U; Pathak, Chandramani; Parmar, Dipak V (2022-01-18)

  Objective: The aim of this study was to screen plant extracts for antimitotic activity using Vigna radiata germination inhibition assay, followed by Allium cepa root tip assay and evaluation of their cytotoxic potential ...
• Surface modified PAMAM dendrimers with gallic acid inhibit, cell proliferation, cell migration and inflammatory response to augment apoptotic cell death in human colon carcinoma cells 

  Priyadarshia, Khushbu; Shirsatha, Kavita; Waghelaa, Bhargav; Sharmaa, Anupama; Pathaka, Ajay Kumarc and Chandramani (2020-07-23)

  To overcome the obstacle of anti-cancer therapy significant attention has been drawn for improving drug delivery system. Since recent past, different approaches were applied using synthetic or natural derivatives for ...
• Cell-Penetrable Peptide-Conjugated FADD Induces Apoptosis and Regulates Inflammatory Signaling in Cancer Cells 

  Ranjan, Kishu; Waghela y, Bhargav N; Vaidya, Foram U (2020-09-19)

  Dysregulated expression of Fas-associated death domain (FADD) is associated with the impediment of various cellular pathways, including apoptosis and inflammation. The adequate cytosolic expression of FADD is critical ...
• Molecular insights of NADPH oxidases and its pathological consequences 

  Waghela, Bhargav N; Vaidya, Foram U; Agrawal, Yashika; Santra, Manas Kumar; Mishra, Vinita (2020-09-01)

  Reactive oxygen species (ROS), formed by the partial reduction of oxygen, were for aong time considered to be a byproduct of cellular metabolism. Since, increase in cellular levels of ROS results in oxidative stress leading ...
• Changes of microbiome in response to supplements with silver nanoparticles in cotton rhizosphere 

  Joshi, A; Joshi, R; Koradiya, P.,; Vank, H. (Journal of Basic Microbiology, 2023)

  The current study focuses on analyzing the effects of supplements containing silver nanoparticles (AgNPs) on plant growth and rhizospheric bacterial communities. Specifically, the impact of AgNP supplements was assessed ...
• Study of Effect of PGPR on Growth and Disease Resistance in Selected Economically Important Crops of Saurashtra Region- India 

  Patel, Shivani D.; Bhattacharya, Chitra; Pandhi, Neepa (Faculty of Science Atmiya University, 2024-01)

  Usages of isolated plant growth promoting rhizobacteria as biofertilizer is an effective alternative for the sustainable agricultural practice to expand soil strength and to enhance the crop productivity of selected ...
• Characterization of Plant Growth-Promoting Activity of Bacteria Isolated from Forest and Coastal Regions of Saurashtra, Gujarat, India 

  Pattani, V. B; Kaneriya, J. P; Joshi, K.,; Sanghvi, G. V (Bioscience Biotechnology Research Communications, 2022)

  The haphazard application of chemical fertilizers and pesticides causes tremendous damage to ecosystems and all biota. One of the most effective ways to tackle the threat is to use biofertilizer. Plant growth promoting ...

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