• Steroid and fatty acid contents from the leaves of Carica Papaya 

  Devmurari, Vishvraj V.; Patel, Poojaben P.; Jadeja, Rajeshreeba A.; Bhadaniya, Cameykumari P.; Aghara, Priti P.; Patel, Anilkumar S.; Tala, Satishkumar D.; Savant, Mahesh M.; Ladva, Kartik D.; Nariya, Pankajkumar B. (Folia Medica(Plovdiv), 2021-06-30)

  Aim: To extract and identify the non-polar entities from the leaves of Carica papaya, a plant used for medicinal purpose as folk medicine. Materials and methods: Petroleum ether extract of the Carica papaya leaves was ...
• Isolation, identification and characterization of degradation impurity of atorvastatin in fixed dose combination of atorvastatin and ezetimibe 

  Desai, Rajesh; Koradiya, Suresh (International Journal of Pharmaceutical Sciences and Drug Research, 2019)

  The objective of this study is to isolation and characterization of unknown degradation product of Atorvastatin calcium in combination formulation product with Ezetimibe by using modern techniques of separation and ...
• Analytical study and impurity profiling of fixed doses combination of amlodipine, hydrochlorothiazide and olmesartan by RP-HPLC and UPLC 

  Desai, Rajesh; Dhalani, Jayesh; Koradiya, Suresh; Nariya, Pankaj (International Journal of Pharmaceutical Sciences and Drug Research, 2022)

  A specific and sensitive reverse phase high pressure liquide chromatography (RP-HPLC) and ultra-performance liquide chromatography (UPLC) method for the determination of related substances for fixed-dose combination ...
• Synthesis and antimicrobial activity of 2-{[(4’-arylidine-5’oxo-2’ phenyl) imidazolyl]-1’-Yl}-3-(4-hydroxyphenyl) propanoic acids 

  Vagadiya, G.V.; Purohit, D.M.; Koradiya, S.B. (Journal of Applicable Chemistry, 2019)

  Derivatives of 5-oxo-imidazoline exhibited good therapeutic activity, with a view of getting to synthesis 2-{[(4'-arylidine-5'-oxo-2'-phenyl)imidazolyl]-1'-yl}-3-(4-hydroxyphenyl) propanoic acids (1a–1n) have been ...
• Synthesis and antimicrobial activity of 2-{[(4’-arylidine-5’oxo-2’ phenyl) imidazolyl]-1’-Yl}-3-keto-1,5-dimethyl-2-phenyl pyrazole 

  Vagadiya, G.V.; Purohit, D.M.; Koradiya, S.B. (Journal of Applicable Chemistry, 2019)

  5-Oxo-imidazoline derivatives exhibited good therapeutic activity, with a view of getting to synthesis 2-{[(4’-arylidine-5’oxo-2’phenyl) imidazolyl]-1’-yl}-3-keto-1,5-dimethyl-2-phenyl pyrazole (1a–1n) have been ...
• Development of Nitromethane catalyzed C-H activation for the preparation of chromeno[3,4-d]imidazol-4-ones as hybrid scaffolds 

  Jain, Vicky; Bijani, Sabera; Ambasana, Pratik; Bhoya, Umed; Shah, Anamik (Chemistry & Biology Interface, 2015)

  Herein we report a tandem cyclization protocol towards hitherto unprepared hybrid scaffolds of coumarin and imidazole core. The synthetic methodology initiates with linking of aromatic amines with coumarin at 4-position, ...
• Isolation and identification of non-polar chemical entity from Leptadenia reticulata aerial parts 

  Dhalani, Jayesh; Dubal, Gaurang; Patel, Anil Kumar; Nariya, Pankajkumar (2019)

  Objective: Leptadenia reticulata is the medicinal plant having many biological activities. It is necessary to find out which types of phytochemical constituents are present in the plant. The objective of this investigation ...
• Etidronic acid catalyzed simple, facile and generalized synthetic protocol for preparation of 2-substituted-1H-benzo[d]imidazole-6-carboxylates 

  Ambasana, Pratik A.; Kapuriya, Naval P.; Nariya, Pankajkumar B.; Naliyapara, Yogesh T.; Vaghasiya, Rajesh G.; Patel, Anilkumar S. (Chemistry & Biology Interface, 2018)

  A facile and efficient cyclo-condensation reaction of substituted ortho-phenylenediamines with an aldehyde or carboxylic acid using etidronic acid to furnish hitherto unreported Methyl 4-methyl-2-sub stituted-1H-benzo[ ...
• Quantum chemical calculations (Ab Initio & DFT), hirshfeld surface analysis, crystal structure and molecular docking study of 2-chloro-4-(4-fluoro-phenyl)-6- isopropyl-pyrimidine-5-carboxylic acid methyl ester 

  Gandhi, Sahaj A.; Patel, Urmila H.; Modh, Rajesh H.; Naliyapara, Yogesh; Patel, Anil S. (Journal of Chemical Crystallography, Springer, 2016)

  Pyrimidine derivatives are well-known nitrogen containing heterocyclic compound which play an important role in medicinal and pharmaceutical applications. The synthesized compound, 2-chloro-4-(4-fluoro-phenyl)-6-isopropy ...
• A convenient synthesis of trisubstituted 1,3,5-triazine derivatives and their antimicrobial screening 

  Cholera, Archana Y.; Ladva, Kartik D. (Der Pharma Chemica, 2018)

  A series of novel 1,3,5-triazine derivatives bearing various aryl amine, 2-amino pyrazine and 4-hydroxy coumarin moieties as substituents have been synthesized by an easy and conventional method using sequential nucleophilic ...
• Facile synthesis of highly functionalized novel pyrazolopyridones using oxoketene dithioacetal and their anti-HIV activity 

  Savant, Mahesh M.; Ladva, Kartik D.; Pandit, Archna B. (Synthetic Communications, Taylor & Francis, 2018-06-08)

  A series of novel 3-amino-4,5-dihydro-6-methyl-4-oxo-N-aryl-1H pyrazolo[4,3-c]pyridine-7-carboxamide have been synthesized starting from various oxoketene dithioacetals. The cyclocondensation reaction of 2-(bis(methy ...
• Design, synthesis, characterization and antimicrobial screening of 4-((4-((6-methylbenzo[d]thiazol-2-yl)amino)-6- (phenylamino)-1,3,5-triazin-2-yl)oxy)-2H-chromen-2- one derivatives 

  Pandit, Archana B.; Ladva, Kartik D. (Journal of Chemistry and Chemical Sciences(An International Research Journal), 2018-06)

  We have described an easy and conventional method for the synthesis of novel 4-hydroxy coumarin, 2-amino-6-methyl benzothiazole and arylamino bearing 1,3,5-triazine derivatives with good to high yields. The reaction of ...
• Stability indicating chromatographic method transfer of immunomodulating drug fingolimod from high performance liquid chromatography to new generation ultra performance liquid chromatography with comparative validation study 

  Ghediya, Ravi V.; Patel, Madhavi.; Pandya, Darshana.; Shah, Anamik.; Khunt, Ranjan C. (Journal of Chemical and Pharmaceutical Research, 2016-03-01)

  The simplest, sensitive, less solvent consuming and time saving stability indicating reverse phase isocratic chromatographic separation method of Fingolimod has been performed on High performance liquid chromatography ...
• Development and validation of Immunomodulating drug Fingolimod by RPHPLC method with detailed force degradation study 

  Ghediya, Ravi V.; Patel, Madhavi.; Pandya, Darshana.; Shah, Anamik.; Khunt, Ranjan C. (Chemistry & Biology Interface, 2016-03-01)

  Fingolimod is a sphingosine -1-phosphate modulator as well as reduces the infiltration of pathogenic lymphocyte cells into the central nervous system because they involved in nervous tissue damage and nerve inflammation. ...
• UV-Vis spectrophotometric assay determination of oral antiplatelet ticagrelor drug in pharmaceutical formulation: Application to content uniformity 

  Pandya, Darshana.; Patel, Madhavi.; Ghediya, Ravi.; Shah, Anamik.; Khunt, Ranjan. (Journal of Chemical and Pharmaceutical Research, 2016-03-01)

  The purpose of this study is to develop and validate a spectroscopic method for the antiplatelet drug, Ticagrelor. The method was performed on Pharmaco-model of UV–Spectrophotometer Shimadzu1700. The method was validated ...
• A Comparative Study on Phyto-Constitutional Profiling of Carica papaya Leaves 

  Devmurari, Vishvraj V.; Bhadaniya, Cameykumari P.; Ambasana, Pratik A. (Journal of Applicable Chemistry, 2018-06-11)

  Carica papaya (Linn) plant is nature's own basket of various phyto-nutrients, and its leaves are used as the most effective supplement in the treatment of dengue fever. It possesses unparallel activity to increase platelet ...
• Isolation and Identification of Non-Polar Chemical Entity from Leptadenia Reticulata Aerial Parts 

  Dhalani, Jayesh.; Dubal, Gaurang.; Patel, Anilkumar.; Nariya, Pankajkumar. (Asian Journal of Pharmaceutical and Clinical Research, 2019-02-01)

  Objective: Leptadenia reticulata is the medicinal plant having many biological activities. It is necessary to find out which types of phytochemical constituents are present in the plant. The objective of this investigation ...
• Synthesis and Biological Screening of 1-{3-[4’- (Dibenzo [B, F] [1, 4] Thiazepin-11”-Yl) Amino] Phenyl}-5-Aryl-1h-Pyrazol-1-Yl-Ethanones 

  Gondaliya, M.V.; Purohit, D.M. (International Journal for Research in Applied Science & Engineering Technology, 2018-01-01)

  Acetyl pyrazoline derivatives procuring shows better therapeutic activity looking at their versatile therapeutic importance and with an aim to getting to synthesize some new pyrazolines. The synthesis of 1-{3-[4’-(diabenzo[b, ...
• Synthesis and Biological Screening of N-{4’-[5”- (ARYL)-1”-H-PYRAZOL-3”-yl] PHENYL}- DIBENZO [b,f][1,4] THIAZEPIN-11-AMINE. 

  Gondaliya, M.V.; Purohit, D.M. (International Journal for Research in Applied Science & Engineering Technology, 2018-01-01)

  Pyrazoline derivatives shows broad spectrum of pharmacological activity with a view of getting to synthesized and evaluated biological screening of N-[4’-(5”-aryl-1”-H-pyrazol-3”-yl)phenyl]dibenzo[b,f][1,4]thiazepin-11-a ...
• Synthesis And Biological Screening Of (E)-3-{[(3′- Difluoromethoxy)-5′-(3″-Methyl)-4″-(2‴, 2‴, 2‴- Trifluoroethoxy)Pyridin-2″-Yl]Methoxyphenyl}-1- Aryl-Prop-2-Ene-1-Ones 

  Kakadiya, Sandip P.; Purohit, Heta D.; Purohit, Dipak M. (World Journal of Pharmaceutical Research, 2017-08-09)

  Chalcones are intermediate compounds to synthesis of many heterocyclic compounds. They are especially interesting for their biological and industrial application. (E)-3-{[(3′-Difluoromethoxy)-5′-(3″-methyl)-4″-(2‴,2‴,2‴- ...

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