A specific and sensitive reverse phase high pressure liquide chromatography (RP-HPLC) and ultra-performance liquide chromatography (UPLC) method for the determination of related substances for fixed-dose combination ...

A series of novel 1,3,5-triazine derivatives bearing various aryl amine, 2-amino pyrazine and 4-hydroxy coumarin moieties as substituents have been synthesized by an easy and conventional method using sequential nucleophilic ...

A series of 2-(1H-benzo[d]imidazol-2-ylthio)-3-(substitutedphenyl)-1-(substitutedphenyl) prop-2-en-1-one 3 (A-L) derivatives have been synthesized via Claisen-schmidt reaction of different aromatic aldehydes with 2- ...

A series of N-(4-(substituted phenyl)thiazol-2-yl)-2-(1-(substituted benzyl or pyridinyl methyl)-1Hbenzo[d]imidazol-2-ylthio)acetamide 4(A-I) & 2-(1H-benzo[d]imidazol-2-ylthio)-N-(5-(substituted phenyl, benzyl)-1,3,4-thi ...

Fingolimod is a sphingosine -1-phosphate modulator as well as reduces the infiltration of pathogenic lymphocyte cells into the central nervous system because they involved in nervous tissue damage and nerve inflammation. ...

Pyrimidine (1:3 Diazine) derivatives showed good biological and therapeutic activities, with a view of getting to synthesized 4-aryl-2-hydroxy-6-{[(3′-Difluoromethoxy)-5′-(3″-methyl)-4″-(2‴,2‴,2‴-trifluoroethoxy)pyridin- ...

A series of novel 3-amino-4,5-dihydro-6-methyl-4-oxo-N-aryl-1H pyrazolo[4,3-c]pyridine-7-carboxamide have been synthesized starting from various oxoketene dithioacetals. The cyclocondensation reaction of 2-(bis(methy ...

Objective: Leptadenia reticulata is the medicinal plant having many biological activities. It is necessary to find out which types of phytochemical constituents are present in the plant. The objective of this investigation ...

The objective of this study is to isolation and characterization of unknown degradation product of Atorvastatin calcium in combination formulation product with Ezetimibe by using modern techniques of separation and ...

Pyrimidine derivatives are well-known nitrogen containing heterocyclic compound which play an important role in medicinal and pharmaceutical applications. The synthesized compound, 2-chloro-4-(4-fluoro-phenyl)-6-isopropy ...