The objective of this study is to isolation and characterization of unknown degradation product of Atorvastatin calcium in combination formulation product with Ezetimibe by using modern techniques of separation and ...

Derivatives of 5-oxo-imidazoline exhibited good therapeutic activity, with a view of getting to synthesis 2-{[(4'-arylidine-5'-oxo-2'-phenyl)imidazolyl]-1'-yl}-3-(4-hydroxyphenyl) propanoic acids (1a–1n) have been ...

Herein we report a tandem cyclization protocol towards hitherto unprepared hybrid scaffolds of coumarin and imidazole core. The synthetic methodology initiates with linking of aromatic amines with coumarin at 4-position, ...

A facile and efficient cyclo-condensation reaction of substituted ortho-phenylenediamines with an aldehyde or carboxylic acid using etidronic acid to furnish hitherto unreported Methyl 4-methyl-2-sub stituted-1H-benzo[ ...

A series of novel 1,3,5-triazine derivatives bearing various aryl amine, 2-amino pyrazine and 4-hydroxy coumarin moieties as substituents have been synthesized by an easy and conventional method using sequential nucleophilic ...

We have described an easy and conventional method for the synthesis of novel 4-hydroxy coumarin, 2-amino-6-methyl benzothiazole and arylamino bearing 1,3,5-triazine derivatives with good to high yields. The reaction of ...

Fingolimod is a sphingosine -1-phosphate modulator as well as reduces the infiltration of pathogenic lymphocyte cells into the central nervous system because they involved in nervous tissue damage and nerve inflammation. ...

Carica papaya (Linn) plant is nature's own basket of various phyto-nutrients, and its leaves are used as the most effective supplement in the treatment of dengue fever. It possesses unparallel activity to increase platelet ...

Acetyl pyrazoline derivatives procuring shows better therapeutic activity looking at their versatile therapeutic importance and with an aim to getting to synthesize some new pyrazolines. The synthesis of 1-{3-[4’-(diabenzo[b, ...

Chalcones are intermediate compounds to synthesis of many heterocyclic compounds. They are especially interesting for their biological and industrial application. (E)-3-{[(3′-Difluoromethoxy)-5′-(3″-methyl)-4″-(2‴,2‴,2‴- ...