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Browsing 01. Journal Articles by Issue Date

Browsing 01. Journal Articles by Issue Date

Now showing items 1-20 of 57

Quorum sensing

Pawar, Shrikant; Lahiri, Chandrajit (Academic Journals, 2018)

Bacterial cells exhibit a complex pattern of co-operative behaviour as shown by their capacity to communicate amongst each other. Quorum sensing (QS) is a generic term used for bacterial cell-to-cell communication which ...
A side-effect free method for identifying cancer drug targets

Ashraf, M. I.; Ong, S. K.; Mujawar, s.; Pawar, S.; More, P.; Paul, S.; Lahiri, Chandrajit (Nature, 2018)

Identifying effective drug targets, with little or no side effects, remains an ever challenging task. A potential pitfall of failing to uncover the correct drug targets, due to side effect of pleiotropic genes, might lead ...
PNMA family

Pang, S. W.; Lahiri, Chandrajit; Poh, C. L.; Tan, Kuan Onn (Elsevier, 2018)

Paraneoplastic Ma Family (PNMA) comprises a growing number of family members which share relatively conserved protein sequences encoded by the human genome and is localized to several human chromosomes, including the ...
Some natural extracts from plants as low-cost alternatives for synthetic PGRs in rose micropropagation

Chauhan, U.; Singh, A. K.; Godani, D.; Handa, S.; Gupta, P S.; Patel, S.; Joshi, P. (Journal of Applied Horticulture, 2018)

Effect of various plant extracts during in vitro culture of rose (Rosa hybrida L. cv. bush rose), with the objective of replacing synthetic Plant Growth regulators (PGRs) to reduce the production cost, was studied. Test ...
Characterization and partial purification of an antibacterial agent from halophilic actinomycetes Kocuria sp. strain rsk4

Kumar, Ravi Ranjan; Jadeja, Vasantba J (BioImpacts, 2018)

Introduction: The inevitable rise of antibiotic-resistant bacteria is a global health problem. These pathogens erode the utility of available antibiotics. Staphylococcus aureus is one of the major causes of community-acquired ...
Some natural extracts from plants as low-cost alternatives for synthetic PGRs in rose micropropagation

Chauhan, Urmi; Singh, Anil Kumar; Godani, Divyesh; Handa, Satish\; Gupta, Praveen S.; Patel, Shivani; Joshi, Preetam (Journal of Applied Horticulture, 2018)

Effect of various plant extracts during in vitro culture of rose (Rosa hybrida L. cv. bush rose), with the objective of replacing synthetic Plant Growth regulators (PGRs) to reduce the production cost, was studied. Test ...
Dual role of Par‐4 in abrogation of EMT and switching on mesenchymal to epithelial transition (MET) in metastatic pancreatic cancer cells

Katoch, Archana; Suklabaidya, Sujit; Chakraborty, Souneek; Nayak, Debasis; Rasool, Reyaz U.; Sharma, Deepak; Mukherjee, Debaraj; Faheem, Mir M.; Kumar, Anmol; Sharma, Parduman R.; Senapati, Shantibhusan; Kumar, Lekha D.; Goswami, Anindya (Wiley/ Molecular carcinogenesis, 2018)

Epithelial-mesenchymal transition (EMT) is a critical event that occurs during the invasion and metastatic spread of cancer cells. Here, we conceive a dual mechanism of Par-4-mediated inhibition of EMT and induction of MET ...
Influential Quorum Sensing Proteins of multidrug resistant Proteus mirabilis causing urinary tract infections

Pawar, Shrikant; Ashra, Md. Izhar; Mujawar, Shama; Lahiri, Chandrajit (Cambridge, 2018-07)

Catheter-associated urinary tract infections (CAUTI) has become an alarming hospital based disease with the increase of multidrug resistance (MDR) strains of Proteus mirabilis. High prevalence of long-term hospital based ...
In silico identification of the indispensable quorum sensing proteins of multidrug resistant Proteus mirabilis

Pawar, S.; Ashraf, M. I.; Mujawar, s.; Mishra, R.; Lahiri, Chandrajit (Frontiers in Cellular and Infection Microbiology, 2018-08-07)

Catheter-associated urinary tract infections (CAUTI) is an alarming hospital based disease with the increase of multidrug resistance (MDR) strains of Proteus mirabilis. Cases of long term hospitalized patients with multiple ...
Paradigm shift in drug re-purposing from phenalenone to phenaleno-furanone to combat multi-drug resistant Salmonella enterica serovar typhi

Mujawar, Sharma; Gatherer, Derek; Lahiri, Chandrajit (Frontiers in cellular and infection microbiology, 2018-11-14)

Over recent years, typhoid fever has gained increasing attention with several cases reporting treatment failure due to multidrug resistant (MDR) strains of Salmonella enterica serovar Typhi. While new drug development ...
Vimentin activation in early apoptotic ncer cells errands survival pathways during DNA damage inducer CPT treatment in colon carcinoma model

Chakraborty, Souneek; Kumar, Aviral; Faheem, Mir Mohd; Katoch, Archana; Kumar, Anmol; Jamwal, Vijay Lakshmi; Nayak, Debasis; Golani, Aparna; Rasool, Reyaz Ur; Ahmad, Syed Mudabir; Jose, Jedy; Kumar, Rakesh; Gandhi, Sumit G; Kumar, Lekha Dinesh; Goswami, Anindya (Springer Nature/Cell Death and Disease, 2019)

Epithelial to mesenchymal transitions (EMT) is a preparatory process for cancer cells to attain motility and further metastasis to distant sites. Majority of DNA damaging drugs have shown to develop EMT as one of the major ...
A decade of sustained selection pressure on two surface sites of the VP1 protein of Enterovirus A71 suggests that immune evasion may be an indirect driver for virulence

Gatherer, D.; Laa poh, Chit; Lahiri, Chandrajit (Nature, 2019-04-01)

Enterovirus A71 (EV-A71) is an emerging pathogen in the Enterovirus A species group. EV-A71 causes hand, foot and mouth disease (HFMD), with virulent variants exhibiting polio-like acute flaccid paralysis and other central ...
Exploiting chitosan and gold nanoparticles for antimycobacterial activity of in silico identified antimicrobial motif of human neutrophil peptide-1

Sharma, Richa; Raghav, Ragini; Rishi, Praveen; Kumari, Priyanka; Sharma, Sadhna; Srivastava, Sudha; Verma, Indu (Springer Nature/ Scientific Repots, 2019-05-27)
Delineating the plausible molecular vaccine candidates and drug targets of multidrug-resistant Acinetobacter baumannii

Mujawarq, S.; Mishra, R.; Pawar, s.; Gatherer, D.; Lahiri, Chandrajit (Frontiers, 2019-06-20)

Nosocomial infections have become alarming with the increase of multidrug-resistant bacterial strains of Acinetobacter baumannii. Being the causative agent in ∼80% of the cases, these pathogenic gram-negative species could ...
Precision medicine and future of cancer treatment

Lahiri, Chandrajit; Pawar, Shrikan; Mishra, Rohit (Precision Cancer Medicine, 2019-12)

Over the last few decades, there has been a deluge in the production of large-scale biological data mainly due to the advances in high-throughput technology. This initiated a paradigm shift on the focus in medical research. ...
SCREENING OF ENDOPHYTIC ACTINOMYCETES FOR CELLULOSE DEGRADATION

Vyas, Meghavi; Das, Mousumi; Kumar, Ravi Ranjan (Vidhyayana-An International Multidisciplinary Peer-Reviewed E-Journal, 2020)

Actinomycetes or Actinobacteria are Gram positive, filamentous, spore forming ahigh GC containing(60-75% in their DNA) prokaryotes. Endophytic Actinomycetes are the microbes living in the inner part of plant tissues and ...
COVID-19: A Bitter Truth

Bhattacharya, Chitra; Kumar Ravi, Ravi Ranjan; Das, Mousumi (RET Academy for International Journals of Multidisciplinary Research, 2020)

The COVID-19 (Coronavirus Disease-19) is extremely contagious and quickly spreadable pathogenic viral infection caused by SARS-CoV- 2, a virus belongs to coronavirus family member. It was appeared abruptly in Wuhan, China; ...
In vitro antimitotic and cytotoxic potential of plant extracts: a comparative study of Mucuna pruriens, Asteracantha longifolia and Sphaeranthus indicus

Gupta, Praveen Suresh; Patel, Shivani (Springer/ Future Journal of Pharmaceutical Sciences, 2020)

Background: Plants have been used in alternative and traditional medicines for the cure of different types of diseases since ancient time. Secondary metabolites from natural sources play a crucial role in the treatment of ...
COVID-19: A bitter truth

Bhattacharya, Chitra; Kumar Ravi, Ravi Ranjan; Das, Mousumi (International Journal of Research in Humanities & Social Sciences, 2020-05)

The COVID-19 (Coronavirus Disease-19) is extremely contagious and quickly spreadable pathogenic viral infection caused by SARS-CoV- 2, a virus belongs to coronavirus family member. It was appeared abruptly in Wuhan, ...
Screening of endophytic actinomycetes for cellulose degradation

Vyas, Meghavi; Das, Mousumi; Kumar, Ravi Ranjan (Vidhyayana - An International Multidisciplinary Research E-Journal, 2020-05)

Actinomycetes or Actinobacteria are Gram positive, filamentous, spore forming ahigh GC containing(60-75% in their DNA) prokaryotes. Endophytic Actinomycetes are the microbes living in the inner part of plant tissues ...

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