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Browsing 01. Journal Articles by Title

Browsing 01. Journal Articles by Title

Now showing items 1-20 of 139

2-Chloroquinolinyl-thiazolidine-2,4-dione Hybrids as Potential α-Amylase Inhibitors: Synthesis, Biological Evaluations, and In Silico Studies

Karmur, S. B.; Dholariya, M. P; Patel, A. S; Karmur, M. B; Maliwal, D; Pissurlenkar, R. R; Kapuriya, N. P. (2024)

Recently, molecular hybridization strategy has paved a way to develop novel lead compounds for the α‐amylase targeted antidiabetic therapy. In this study, we disclosed a series of new hybrids of thiazolidine‐2,4‐diones ...
A. S.

Ambasana, P. A.; Kapuriya, N. P.; Naliyapara, P. B.; Vaghasiya, Y. T.; Patel, A. S. (Chemistry & Biology Interface, 2018)

Ambasana, P. A., Kapuriya, N. P., Nariya, P. B., Naliyapara, Y. T., Vaghasiya, R. G., & Patel, A. S. (2018). Etidronic acid catalyzed simple, facile and generalized synthetic protocol for preparation of 2-substituted-1H-benzo ...
Aerobic oxidative alkynylation of H-phosphonates and amides: an efficient route for the synthesis of alkynylphosphonates and ynamides using a recyclable Cu–MnO catalyst

Singh, Harshvardhan; Sahoo, Tapan; Sen, Chiranjit; Galani, Sunil M.; Ghosh, Subhash Chandra (The Royal Society of Chemistry / Catalysis Science & Technology, 2019)

An atom-economical and efficient route for the synthesis of alkynylphosphonates and ynamides by aerobic oxidative alkynylation of H-phosphonates and amides with both aliphatic and aromatic alkynes using our synthesized ...
Ameliorative effects of Triphala on mucosal damage in rat model of ulcerative colitis

Nariya, Mukeshkumar; Nariya, Pankaj; Ravishankara, Basavaiah; Goswami, Sunita (2021-04-19)

In Ayurvedic practice, Triphala is widely used in gastric problems including constipation, large intestinal inflammation and colitis. The present research was planned to assess the ameliorative effects of Triphala ...
Analytical study and impurity profiling of fixed doses combination of amlodipine, hydrochlorothiazide and olmesartan by RP-HPLC and UPLC

Desai, Rajesh; Dhalani, Jayesh; Koradiya, Suresh; Nariya, Pankaj (International Journal of Pharmaceutical Sciences and Drug Research, 2022)

A specific and sensitive reverse phase high pressure liquide chromatography (RP-HPLC) and ultra- performance liquide chromatography (UPLC) method for the determination of related substances for fixed-dose combination ...
Analytical Study and Impurity Profiling of Fixed Doses Combination of Amlodipine, Hydrochlorothiazide and Olmesartan by RP-HPLC and UPLC

Desai, Rajesh; Dhalani, Jayesh; Koradia, Suresh; Nariya, Pankaj (2022-01-30)

A specific and sensitive reverse phase high pressure liquide chromatography (RP-HPLC) and ultra-performance liquide chromatography (UPLC) method for the determination of related substances for fixed-dose combination ...
Anti-cancer Investigation of Newly Derived Alicyclic ring and Morpholine Supported Hybrid Molecules by Industrially viable Route

Kapadiya, K .; Pandya, M.; Rathod, C.; Dhalani, J.; Dhaduk, B. (Journal of Scientific & Industrial Research, 2018)

In an attempt to design and synthesize a new class of anticancer molecules, we have reported coupling of aryl aldehyde, p-toluidine and morpholine based isocyanide with cyclopropane carboxylic acid to generate a small ...
Anticancer evaluation of 1, 5-disubstituted tetrazoles using Ugi-azide four-component reactions (UA-4CRs)

Pandit, Chintan; Dholaria, P.; Kapadiya, Khushal (Asian Journal of Organic & Medicinal Chemistry, 2019)

Azide isocyanide-based multicomponent reactions allow the construction of relatively complex molecules through a one-pot synthesis. The proposed reactions have been coupled of four classes of compounds including ...
Biorelevant dissolution studies of platelet aggregation inhibitor: Ticagrelor hydrochloride and its co-crystal with sodium salt of Aspiri

Ambasana, M. A; Kapuriya, N. P.; Ambasana, P. A.; Bhalodia, J.; Bapodra, A. H. (Indian Journal of Chemical Technology, 2022)

The comparative dissolution characteristics of poorly soluble platelet aggregation inhibitor Ticagrelor hydrochloride and its co-crystal with sodium salt of Aspirin in biorelevant media have been demonstrated. The API and ...
A Comparative Study on Phyto-Constitutional Profiling of Carica papaya Leaves

Devmurari, Vishvraj V.; Cameykumari, P; Bhadaniya; Ambasana, Pratik A. (Journal of Applicable Chemistry, 2018-06-11)

Carica papaya (Linn) plant is nature's own basket of various phyto-nutrients, and its leaves are used the most effective supplement in the treatment of dengue fever. It possesses unparallel activity to platelet counts in ...
A Convenient Synthesis of Trisubstituted 1,3,5-triazine Derivatives and their Antimicrobial Screening

Cholera, Archana Y; Ladva, Kartik D (2018)

A series of novel 1,3,5-triazine derivatives bearing various aryl amine, 2-amino pyrazine and 4-hydroxy coumarin moieties as substituents have been synthesized by an easy and conventional method using sequential nucleophilic ...
Correlation study between “structure and commencement temperature” of nematogenic mesomorphs having Azo-Ester linkage

Baku, Neha K.; Cholera, Archana Y.; Travadi, J.J. (World Scientific News, 2023-03-02)

Correlation study between ‘commencement of Nematic Transition Temperature (NTT)’ and their ‘structural property data set’ is carry out. Stepwise backward regression analysis method is applied to find out good correlation ...
Correlation study between “structure and commencement temperature” of nematogenic mesomorphs having Azo-Ester linkage

Baku, Neha K.; Cholera, Archana Y.; Travadi, J. J. (World Scientific News, 2023)

Correlation study between ‘commencement of Nematic Transition Temperature (NTT)’ and their ‘structural property data set’ is carry out. Stepwise backward regression analysis method is applied to find out good correlation ...
Cu(II) heterochelates: Synthesis, spectroscopic, thermal and in-vitro biological studies

Raja, M.N.; Jani, D.H.; Koradiya, S. (Journal of Applicable Chemistry, 2019)

Novel organic based compound 4-Acyl pyrazolone derivatives and their thermal and biological activities were investigated. A new series of Bis-pyrazolone containing ligand and their Cu(II) based heterochelate were ...
Design and rapid microwave irradiated one-pot synthesis of tetrahydropyrimidine derivatives and their screening in vitro antidiabetic activity

Lalpara, J. N.; Hadiyal, S. D.; Radia, A. J.; Dhalani, J. M.; Dubal, G. G. (Taylor & Francis Group, LLC / Polycyclic Aromatic Compounds, 2020-12-01)

A rapid and efficient method has been developed for one-pot synthesis of some newly designed tetrahydropyrimidine derivatives with aid of 1,3,4-oxadiazole containing aldehyde, substituted acetoacetanilide and thiourea/guanidine ...
Design and synthesis of 1, 2-bis (hydroxymethyl) pyrrolo [2, 1-a] phthalazine hybrids as potent anticancer agents that inhibit angiogenesis and induce DNA interstrand cross-links.

Jain, S. M.; Chen, T. L; Patel, A. S; Pidugu, H. B.; Lin, Y. W.; Lee, T. C. (ACS Publications, 2019)

Hybrid molecules are composed of two pharmacophores with different biological activities. Here, we conjugated phthalazine moieties (antiangiogenetic pharmacophore) and bis(hydroxymethyl)pyrrole moieties (DNA cross-linking ...
Design and Synthesis of Some Novel Thiazole Molecules

Jadeja, Jaysinh I.; Savant, Mahesh M. (International Journal of Pharmaceutical Sciences and Research, 2023)

A series of novel (Z)-3-((5-(2-((E)-arylidene) hydrazine-1- carbonyl)-4-methylthiazol-2-yl)amino)-2-cyano-3-(methylthio) acrylate 4a-t molecules have been synthesized and characterized by 1H NMR, 13C NMRand mass spectral ...
Design, Synthesis and Antidiabetic Activity of Biphenylcarbonitrile-Thiazolidinedione Conjugates as Potential α-Amylase Inhibitors

Rathod, Chirag H; Nariya, Pankajkumar B.; Maliwal, Deepika; Pissurlenkar, Raghuvir RS; Kapuriya, Naval P.; Patel, Anilkumar S (2021-02-24)

The á-amylase inhibition has been considered as an effective therapeutic approach against chronic Type 2 Diabetes mellitus (DM). In the present study, a series of biphenylcarbonitrilethiazolidinedione conjugates have ...
Design, Synthesis and Antidiabetic Activity of Biphenylcarbonitrile‐Thiazolidinedione Conjugates as Potential α‐Amylase Inhibitors.

Rathod, C. H.; Nariya, P. B.; Maliwal, D.Pissurlenkar; Kapuriya, R. R.; Patel, A. S. (ChemistrySelect, 2021)

Abstract The α‐amylase inhibition has been considered as an effective therapeutic approach against chronic Type 2 Diabetes mellitus (DM). In the present study, a series of biphenylcarbonitrile‐thiazolidinedione conjugates ...
Design, synthesis and antitumour evaluation of pyrrolo [1, 2-f]-phenanthridine and dibenzo [f, h] pyrrolo [1, 2-b] isoquinoline derivatives

Patel, A.S.; Jain, V; Rao, V.N.; Lin, Y.W.; Shah, A; Lai, K.C.; Su, T.L.; Lee, TC (European Journal of Medicinal Chemistry, 2020)

Abstract A series of 1,2-bis(hydroxymethyl)pyrrolo[1,2-f]phenanthridine derivatives and their alkyl (ethyl and isopropyl) carbamates and 12,13-bis(hydroxymethyl)-9,14-dihydro-dibenzo[f,h]pyrrolo[1,2-b]isoquinoline derivatives ...

Now showing items 1-20 of 139

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