• Prevalence of tuberculosis and drug--resistant tuberculosis in tertiary care rural hospital in Gujarat, India: a retrospective study 

  Ughreja, Reena; Bhatt, Vaibhav; Shah, Sunny; Boxa, Devang (European Journal of Translational and Clinical Medicine, 2023)

  Background: Mycobacterium tuberculosis causes tuberculosis (TB), the most lethal infectious disease in the world that affects people of all ages. The aim of our study was to estimate the prevalence of TB in the Gujarat state ...
• Code of Conduct & Professional Ethics in Higher Education Institutions 

  Bansal Agarwal, Aayushi (Edulink: Journal of Education, 2023)

  The purpose of this text is to lay out a framework for codes of practice for ethical conduct in higher education institutions. In order to achieve the intended aims and objectives, professional ethics are thought to be of ...
• Development of rapidly soluble mebendazole nanosuspension forcolorectal cancer 

  Patel, Rajeshri D.; Patel, Akanksha S.; Patel, Henis J.; Sarvepalli, Sruthi; Patel, Ketan D. (Journal of Drug Delivery Science and Technology, 2024)

  Mebendazole (MBZ) has been proven as a repurposing molecule against colorectal cancer. Unfortunately, its clinical application isconstrained by its extremely poor solubility and bioavailability. The aim of the current work ...
• A Concise Review on Characteristics and Analytical Methods of Paroxetine 

  Patel, Rajeshri D.; Desai, Kushani N.; Godhani, Dhruvi B.; Panchal, Prachi A. (Inventi Rapid: Pharm Analysis & Quality Assurance, 2021)

  Paroxetine (PAX) is a powerful and selective serotonin reuptake inhibitor (SSRI) with some neuropharmacological properties used mainly for the treatment of anxiety and depression. Due to the first pass degradation, PAX ...
• A Short Review on Analysis of Itraconazole in Bulk Drug and in Pharmaceutical Dosage Form 

  Patel, Rajeshri D.; Majethiya, Harshil Y.; Sakariya, Ashish B.; Jadav, Yashpal (Inventi Rapid: Pharm Analysis & Quality Assurance, 2021)

  Itraconazole (ITZ) is an antifungal triazole, used to treat systemic and superficial fungal infections. Its clinical effectiveness is limited due to its low water solubility which results in poor bioavailability. Therefore, ...
• Application of a Validated RP-HPLC Method in Solubility and Dissolution Testing for Simultaneous Estimation of Diacerein and Its Active Metabolite Rhein in Presence of Coformers in the Eutectic Tablet Formulation 

  Patel, Rajeshri D.; Raval, Mihir K.; Pethani, Trupesh M. (Journal of Chromatographic Science, 2020)

  The present study aimed to develop and validate a novel reversed-phase high-performance liquid chromatography method for simultaneous estimation of Diacerein (DIA) and Rhein (Rh, alkaline degradation product and active ...
• Formulation of Diacerein Cocrystal Using β-Resorcylic Acid for Improvement of Physicomechanical and Biopharmaceutical Properties 

  Patel, Rajeshri D.; Raval, Mihir K. (OPRD, 2020-10-28)

  Diacerein (DIA) is an approved treatment for osteoarthritis. However, its clinical effectiveness is limited because of its poor aqueous solubility, which causes bioavailability issues. The current study aimed to augment ...
• Formation of Diacerein − fumaric acid eutectic as a multi-component system for the functionality enhancement 

  Patela, Rajeshri D.; Ravala, Mihir K.; Shethb, Navin R. (Journal of Drug Delivery Science and Technology, 2020-02-04)

  The present study aimed to enhance physico-mechanical properties of poorly soluble drug Diacerein (DIA) using crystal engineering approach. Fumaric acid (FMA) was competent enough to generate a novel solid form of DIA by ...
• Tamoxifen: An Investigative Review for Nano Dosage Forms and Hyphenated Techniques 

  Patel, Rajeshri Dineshbhai; Bhalani, Yamini Anilbhai; Sudani, Dhruti Sanjaybhai; Vachhani, Lipsa Ashvinbai (2022)

  Tamoxifen (TAM), a non-steroidal antiestrogen, has revolutionized female breast cancer treatment. The mechanism involves is to compete with 17β-estradiol (E2) at the receptor site and blocking the promotional role of E2 ...
• Reviewing the recent advancements of Terminalia arjuna, the guardian of the Heart 

  Agarwal Bansal, Aayushi; Chhatrala, Kelsi A.; Thakur, Shikha (International Journal of Green and Herbal Chemistry, 2023-11)

  An herb that is anti-oxidant, lowers cholesterol and blood pressure, and helps with diabetes all at once – Terminalia arjuna, it is. Since ancient times, medicinal plants have been a significant source of therapeutic ...
• Microfluidic Organ-On-A-Chip Models of Human organs in Drug Discovery 

  Nandy, Shouvikkumar; Thakur, Shikha; Saha, Sujata; Chhatrala, Kelsi A.; Agarwal Bansal, Aayushi (Journal of Emerging Technologies and Innovative Research(JETIR), 2024-03)

  Recent years have seen a rise in interest in microfluidics phenomena as scientists have taken advantage of their special qualities to create better design options. Over the past few years, there has been an increase in ...
• To Formulate Film Forming Spray using Quercus Infectoria (Oak Gall) for Wound Healing Activity 

  Sorathiya, Sahil; Patel, Samixa R. (International Journal of Innovative Science and Research Technology, 2023-11)

  Natural resource-derived compounds have been used in traditional medicine for as long as anybody can remember to influence the wound healing process. In compared to modern pharmaceuticals, these substances have a reduced ...
• A Rapid RP-Hplc Stability Method Development & Validation For Antiviral HIV Drugs Cabotegravir & Rilpivirine In I.M. Injection 

  Pandya, Yogi; Patel, Samixa (International Journal of Biology, Pharmacy and Allied Sciences (IJBPAS), 2023-03)

  In pharmaceutical analysis for the medicinal agents & dosage forms new sophisticated chromatographic methods are utilized for the quality control purpose. There are necessities for new medicinal agents for the treatment ...
• Phyto-pharmaceuticals as a safe and potential alternative in management of psoriasis: a review 

  Patel, Priya; Garala, Kevinkumar C.; Bagada, Arti; Singh, Sudarshan; Prajapati, Bhupendra G.; Kapoor, Devesh (DE Gruyter, 2024-11-12)

  Psoriasis is a chronic autoimmune skin disease with a worldwide prevalence of 1–3 % results from uncontrolled proliferation of keratinocytes and affects millions of people. While there are various treatment options ...
• Understanding the Effect of Floral Waste Biocompost and Agnihotra ash on Soil Fertility and Plant Growth using Central Composite Design. Ecology 

  Patel, Sarvangi; Gorasiya, Tejas H.; Garala, Kevin; Faldu, Nilkanth (Environment and Conservation Journal Papers, 2023-03-31)

  Enormous measures of flowers are presented in temples in India making a lot of floral waste. The temple squanders are delivered in the water bodies or unloaded at the accessible spots of land which makes extreme environmental ...
• Formulation and Evaluation of Sustain Release Matrix Based Tablet of Ketorolac Tromethamine Using Tamarind Gum and Tapioca Starch Natural Polymers As Release Modifiers 

  Buddhadev, Sheetal S.; Garala, Kevinkumar C.; Buddhadev, Sandip (Educational Administration: Theory and Practice, 2024-03-30)

  The objective of the study was to formulate ketorolac tromethamine, a non-steroidal anti-inflammatory drug, into a sustained-release tablet. Using the wet granulation method, tamarind gum, tapioca starch, and chitosan, ...
• Unlocking the Potential of RNA Nanoparticles: A Breakthrough Approach to Overcoming Challenges in Colon Cancer Treatment 

  Karati, Dipanjan; Mukherjee, Swarupananda; Basu, Biswajit; Garala, Kevinkumar; Dutta, Ayon; Prajapati, Bhupendra G.; Bhattacharya, Sankha (Current Pharmaceutical Biotechnology, 2024-03-13)

  Globally, one of the leading causes of cancer-related deaths is colon cancer. As this form of cancer has a tremendous potential to metastasize, effective treatment is complicated and sometimes impossible. Despite the ...
• Lipid-Based Nanoparticles in Delivering Bioactive Compounds for Improving Therapeutic Efficacy 

  Patel, Priya; Garala, Kevinkumar C.; Singh, Sudarshan; Prajapati, Bhupendra G.; Chittasupho, Chuda (Pharmaceuticals, 2024-03-01)

  In recent years, due to their distinctive and adaptable therapeutic effects, many natural bioactive compounds have been commonly used to treat diseases. Their limited solubility, low bioavailability, inadequate ...
• Advanced Targeted Drug Delivery of Bioactive Nanomaterials in the Management of Cancer 

  Basu, Biswajit; Garala, Kevinkumar C.; Patel, Rajeshri; Dutta, Ayon (Current Medicinal Chemistry, 2024)

  Cancer is defined as the unchecked expansion of aberrant cells. Radiation, chemotherapy, and surgery are currently used in combination to treat cancer. Traditional drug delivery techniques kill healthy proliferating cells ...
• Quality by design aided self-nano emulsifying drug delivery systems development for the oral delivery of Benidipine: Improvement of biopharmaceutical performance 

  Buddhadev, Sheetal S.; Garala, Kevinkumar C.; Saisivam, S.; Rahamathulla, Mohamed; Mohammed Muqtader, Ahmed; Syeda Farhana, Ayesha; Pasha, Ismail (Drug Delivery (Taylor & Francis), 2024)

  The primary objective of the research effort is to establish efficient solid self-nanoemulsifying drug delivery systems (S-SNEDDS) for benidipine (BD) through the systematic application of a quality-bydesign (QbD)-based ...

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