01. Journal Articles: Recent submissions

Now showing items 41-60 of 97

Development and validation of zero absorbance method for simultaneous estimation of aliskiren and amlodipine in combined dosage form

Patel, Samixa; Patel, Chhaganbhai (Asian Pharma Press, 2016)

A simple, accurate, precise, economical and reproducible method was developed for simultaneous estimation of aliskiren and amlodipine in Combined Pharmaceutical Dosage Forms. The excipients in the commercial tablet preparation ...
Development and Validation of Spectrophotometric Method for Determination of Aliskiren, Amlodipine and Hydrochlorothiazide in combined Pharmaceutical Dosage Forms

Patel, Samixa; Patel, Chhaganbhai (Asian Pharma Press, 2014)

A simple, accurate, precise, economical and reproducible method was developed for simultaneous estimation of aliskiren, amlodipine and hydrochlorothiazide in Combined Pharmaceutical Dosage Forms. The excipients in the ...
Amlodipine: A Review of Analytical Methods

Patel, Samixa; Patel, Chhaganbhai (Inventi Journals, 2012-05)

Amlodipine is a long-acting calcium channel blocker (dihydropyridine (DHP) class) used as an anti-hypertensive and in the treatment of angina. Like other calcium channel blockers, amlodipine acts by relaxing the smooth ...
Development and validation of spectrophotometric method for determination of Olmesartan, amlodipine and hydrochlorothiazide in combined pharmaceutical dosage forms

Patel, Samixa; Patel, Chhaganbhai (Novel Science International Journal of Pharmaceutical Science, 2012)

A simple, accurate, precise, economical and reproducible method was developed for simultaneous estimation of olmesartan, amlodipine and hydrochlorothiazide in Combined Pharmaceutical Dosage Forms. The excipients in the ...
Simultaneous Determination of Nebivolol and Amlodipine in Combined Dosage Form by Derivative Spectrophotometry

Patel, Samixa; Patel, Shweta; Patel, Jignesh; Patel, Paresh (Research J. Pharm. and Tech., 2011-01)

Simple and accurate method to determine Nebivolol and Amlodipine, in tablet dosage form, was developed and validated using Derivative Spectrophotometry. Derivative spectrophotometric method was based on the determination of ...
Development and Validation of High-Performance Thin-Layer Chromatography Method for Determination of Nebivolol and Amlodipine besylate in Combined Dosage Forms

Patel, Samixa; Patel, Shweta; Patel, Jignesh; Patel, Paresh (Journal of Pharmacy Research, 2010-01)

The manuscript describes validated High-Performance Thin-Layer Chromatography (HPTLC) method for the estimation of Nebivolol (NEB) and Amlodipine (AML) in combined dosage form. The HPTLC separation was achieved on an ...
Synthesis and Evaluation of Some Novel Substituted 1, 3, 4- Oxadiazole and Pyrazole Derivatives for Antifungal Activity

Rabara, Parag; Jivani, Nurudin; Pattan, Shashikant; Garala, Kevin (Inventi Journals, 2016)

A series of 1,3,4-oxadiazole and pyrazole derivatives have been synthesized and evaluated for antifungal activity. The structures of synthesized compounds were confirmed by IR, 1H NMR, Mass and CHN analysis. These compounds ...
Formulation and Characterization of Taste Masked Mouth Dissolving Tablets of Tramadol HCl Using Different Approaches

Garala, Kevin; Patel, Anjali; Rabara, Parag (Inventi Journals, 2016)

To overcome difficulty in swallowing tablets or capsules, scientists have considerably dedicated their effort to develop novel drug delivery systems which enhance safety and efficacy of drug molecule and to achieve ...
Formulation and Development of W/O Type Microemulsion based Transdermal Systems for Verapamil Hydrochloride

Dhingani, Anjali; Patel, Jaydeep; Garala, Kevin; Patel, Hardik; Dharamsi, Abhay (Inventi Journals, 2013)

The aim of the present investigation was to design and develop a novel microemulsion (ME) based transdermal drug delivery system of highly water soluble drug, verapamil HCl (VPLH) to enhance its therapeutic efficacy. ...
A Review on Solid Self Emulsifying Drug Delivery Systems and Dosage Forms

Dholakiya, Arpana; Shah, Akash; Jakasania, Pratik; Patel, Jaydeep; Garala, Kevin (Inventi Journals, 2013)

Combinatorial chemistry and high-throughput screening used in drug discovery have resulted in a 70% of new drug candidates shown poor aqueous solubility in recent years which leads to low oral bioavailability. In clinical ...
Formulation and Development of Microemulsion Based Gel (Mbg) of Ibuprofen for Topical Drug Delivery

Shah, Akash; Vyas, Kalyani; Aviya, Ketan; Jivani, Pankti; Dobariya, Vishal; Patel, Jaydeep; Garala, Kevin (Inventi Journals, 2013)

The aim of the present study was to formulate an Ibuprofen loaded microemulsion based gel (MBG) for the topical delivery. The oil phase selected for the preparation of stable microemulsion was IsoPropyl Myristate (IPM). ...
Development and Validation of RP-HPLC Method for Simulataneous Estimation of Lercanidipine HCl and Atenolol in Pharmaceutical Formulations

Dhingani, A.; Patel, J.; Garala, K.; Dharamsi, A. (Inventi Journals, 2012)

A simple, precise and RP-HPLC (reverse phase – high performance liquid chromatographic) method was developed and validated for the simultaneous determination of lercanidipine HCl (LDPH) and atenolol (AT) in pharmaceutical ...
Overcoming Limitations in Dissolution Testing of Poorly Water Soluble Racecadotril

Garala, K.; Patel, J.; Dhingani, A.; Raval, M.; Dharamsi, A. (Inventi Journals, 2012)

The conventional dissolution test, particularly the USP apparatus I and II, remains an important tool in the field of the pharmaceutical product development. For accurate dissolution characterization, sink conditions, ...
Development and Validation of A Rapid and Sensitive HPLC Method for Estimation of Racecadotril

G., Kevin; Patel, J.; Dhingani, A.; Raval, M.; Dharamsi, A. (Inventi Journals, 2012)

: A simple, specific, sensitive and rapid reverse phase high performance liquid chromatographic (HPLC) method for the determination of racecadotril (RCD) was developed and validated. Sample preparation involved simple ...
Design and Evaluation of Transdermal Drug Delivery System of Nebivolol Hydrochloride

Garala, K.; Kapadiya, M.; Patel, J.; Patel, A.; Raval, M.; Dharamsi, A. (Inventi Journals, 2013)

Nebivolol hydrochloride is a selective β1-receptor antagonist with antihypertensive properties having plasma half life of 10 h and 12 % oral bioavailability. In the present work transdermal matrix patches of Nebivolol ...
Solubility Enhancement of Candesartan by Polyamidoamine Dendrimers

Patel, Jaydeep; Garala, Kevin; Dhingani, Anjali; Raval, Mihir; Dharamsi, Abhay (Inventi Journals, 2012)

The present study was aimed for solubility enhancement of candesartan (CND) by dendrimers. The aqueous solubility of CND was measured in the presence of dendrimers in distilled water. The effect of variables (pH condition, ...
An Emerging Trend in Oral Drug Delivery Technology : Rapid Disintegrating Tablets

Mehta, Kuldeep; Garala, Kevin; Basu, Biswajit; Bhalodia, Ravi; Joshi, Bhavik; Charyulu, R. Narayana (Journal of Pharmaceutical Science and Technology, 2010)

Recent advances in novel drug delivery system aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach ...
Physical Penetration Enhancement Through TDDS: A Review

Garala, Kevin; Basu, Biswajit; Dharamsi, Abhay (Journal of Pharmacy Research, 2010)

The delivery of drugs into systemic circulation via skin has generated lot of interest in recent time. Transdermal drug delivery is now a promising route of drug delivery system. The transdermal drug delivery system has ...
Lycopene: A novel anti-oxidant and anticancer agent

Basu, Biswajit; Garala, Kevin; Dharamsi, Abhay (Journal of Pharmacy Research, 2010)

Prostate cancer is a major public health problem in nations that have an affluent culture with an aging population. Over the last decade the development of chemopreowering the risk of prostate cancer. Lycopene is the most ...
Formulation and Evaluation of Pimozide Buccal Mucoadhesive Patches

Basu, Biswajit; Garala, Kevin; Thimmasetty, J. (International Journal of Pharmaceutical Sciences and Nanotechnology, 2010-03)

Within the oral mucosal cavity, the buccal region offers an attractive route of administration for systemic drug delivery. Pimozide patches were prepared using HPMC (15 & 47 cPs), carbopol 934, poly vinyl alcohol, and ...

Now showing items 41-60 of 97

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