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An Efficient and Facile Synthesis of 4-Aryl-2- Hydroxy-6-{[(3′-Difluoromethoxy)-5′-(3″-Methyl)- 4″-(2‴, 2‴, 2‴-Trifluoroethoxy) Pyridin-2″-Yl] Methoxyphenyl}-1-6-Dihy Dropyrimidines.
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| dc.contributor.author | Kakadiya, Sandip P. | |
| dc.contributor.author | Purohit, Heta D. | |
| dc.contributor.author | Vekariya, Nutan B. | |
| dc.contributor.author | Patel, Piyush A. | |
| dc.contributor.author | Joshi, Asha K. | |
| dc.contributor.author | Purohit, Dipak M. | |
| dc.date.accessioned | 2021-08-18T10:18:22Z | |
| dc.date.available | 2021-08-18T10:18:22Z | |
| dc.date.issued | 2017-10-01 | |
| dc.identifier.citation | Kakadiya, S. P., Purohit, H. D., Vekariya, N. B., Patel, P. A., Joshi, A. K., & Purohit, D. M. (2017). An Efficient and Facile Synthesis of 4-Aryl-2-Hydroxy-6-{[(3′-Difluoromethoxy)-5′-(3 ″-Methyl)-4 ″-(2‴, 2‴, 2‴-Trifluoroethoxy) Pyridin-2 ″-Yl] Methoxyphenyl}-1-6-Dihy Dropyrimidines.International Journal for Research in Applied Science & Engineering Technology, 5(10), | en_US |
| dc.identifier.issn | 2321-9653 | |
| dc.identifier.uri | https://www.ijraset.com/archive-detail.php?AID=62 | |
| dc.identifier.uri | http://10.9.150.37:8080/dspace//handle/atmiyauni/694 | |
| dc.description.abstract | Pyrimidine (1:3 Diazine) derivatives showed good biological and therapeutic activities, with a view of getting to synthesized 4-aryl-2-hydroxy-6-{[(3′-Difluoromethoxy)-5′-(3″-methyl)-4″-(2‴,2‴,2‴-trifluoroethoxy)pyridin-2″-yl]methoxyphenyl}-1-6-dihydropyrimidines (3a-3k) by the cyclo condensation of (E)-3-{[(3′-Difluoromethoxy)-5′-(3″-methyl)-4″- (2‴,2‴,2‴-trifluoroethoxy)pyridine-2-yl]methoxyphenyl}-1-aryl-prop-2-ene-1-ones with urea in presence of alcoholic KOH. All Synthesized compounds characterized by TLC, IR, 1HNMR, Mass spectra and Physical constants. All the synthesized compounds screened for their antimicrobial activity against Gram +ve bacteria (B.mega,B.Subtillis), Gram -vebacteria(E.coli,P.fluorescens) and fungi (A.awamori). | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | International Journal for Research in Applied Science & Engineering Technology | en_US |
| dc.subject | 4-Aryl-2-hydroxy-6-{[(3′-difluoromethoxy)-5′-(3′′-methyl)-4′′-(2′′′,2′′′,2′′′-trifluoroethoxy)pyridin-2′′- yl]methoxyphenyl}-1,6-dihydropyrimidines,(E)-3-{[(3′-Difluoromethoxy)-5′-(3″-methyl)-4″-(2‴,2‴,2‴-trifluoroethoxy) pyridin- 2″-yl]methoxyphenyl}-1-aryl-prop-2-ene-1-ones,Aromatic Ketone,Urea(Heterocyclic Compounds) | en_US |
| dc.title | An Efficient and Facile Synthesis of 4-Aryl-2- Hydroxy-6-{[(3′-Difluoromethoxy)-5′-(3″-Methyl)- 4″-(2‴, 2‴, 2‴-Trifluoroethoxy) Pyridin-2″-Yl] Methoxyphenyl}-1-6-Dihy Dropyrimidines. | en_US |
| dc.type | Article | en_US |
