Abstract:
Pyrazoline derivatives shows broad spectrum of pharmacological activity with a view of getting to synthesized and evaluated biological screening of N-[4’-(5”-aryl-1”-H-pyrazol-3”-yl)phenyl]dibenzo[b,f][1,4]thiazepin-11-amine(5a-5j).The compound(5a-5j) have been synthesized by the condensation of 1”-[4’-diabenzo[b,f][1,4] thiazepin-11-yl)aminophenyl]-3”-aryl-2-ene-l”-ones with hydrazine hydrate. The constitutions of the synthesized products were supported by IR, 1H NMR and mass spectral data. The products were screened for their antimicrobial activity at 50 μg concentration by cup-plate method.
