Synthesis of pyrrole derivatives via cycloaddition reaction  of reissert hydrofluoroborate salts with α-bromoacrylamides

Rathod, Chirag H.; Patel, Anilkumar S.

dc.contributor.author	Rathod, Chirag H.
dc.contributor.author	Patel, Anilkumar S.
dc.date.accessioned	2023-05-08T03:09:58Z
dc.date.available	2023-05-08T03:09:58Z
dc.date.issued	2021
dc.identifier.citation	Rathod, C. H., & Patel, A. S. (2021). Synthesis of Pyrrole Derivatives via Cycloaddition Reaction of Reissert Hydrofluoroborate Salts with α-Bromoacrylamides. Analytical Chemistry Letters, 11(3), 289-302.	en_US
dc.identifier.issn	2230-7532
dc.identifier.uri	http://10.9.150.37:8080/dspace//handle/atmiyauni/861
dc.description	Authors are thankful to the School of Science, RK University & Faculty of Science, Atmiya University, Rajkot for providing a laboratory experiment facility. We also thank to the Central Instrumental facility (CIF), Shree M. & N. Virani Science College (Autonomous) for providing spectral analysis.	en_US
dc.description.abstract	An investigation of α-bromoacrylamide as a dienophile for the cycloaddition reaction of Reissert hydrofluoroborate salt of quinoline/phenanthridine has been carried out. The optimized condition has been developed for the [4+2] cycloaddition reaction of Reissert hydrofluroborate salt and a-bromoacrylamide by using K2 CO3 in DMF under moderate temperature to afford highly functionalized pyrrole derivatives (6a-f and 7a-f) in very good to excellent yield. The structures of newly synthesized compounds were established based on FT-IR, Mass, 1 H and 13C NMR spectral techniques. Besides, the structure of compound 7a has been confirmed by 2D NMR experiments (COSY and HSQC).	en_US
dc.language.iso	en	en_US
dc.publisher	Analytical Chemistry Letters, Taylor & Francis	en_US
dc.subject	Reissert hydrofluoroborate salt	en_US
dc.subject	Pyrrole derivatives	en_US
dc.subject	Cycloaddition reaction	en_US
dc.subject	α-Bromoacrylamides	en_US
dc.title	Synthesis of pyrrole derivatives via cycloaddition reaction of reissert hydrofluoroborate salts with α-bromoacrylamides	en_US
dc.type	Article	en_US