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Facile synthesis of (E)-5-styrylpyrimidines via wittig reaction using sodium tripolyphosphate in water

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dc.contributor.author Patel, Anilkumar S.
dc.contributor.author Gandhi, Sahaj A.
dc.contributor.author Modh, Rajesh D.
dc.contributor.author Patel, Urmila H.
dc.contributor.author Naliapara, Yogesh T.
dc.contributor.author Kapuriya, Naval P.
dc.date.accessioned 2023-05-08T03:20:16Z
dc.date.available 2023-05-08T03:20:16Z
dc.date.issued 2021
dc.identifier.citation Patel, A. S., Gandhi, S. A., Modh, R. D., Patel, U. H., Naliapara, Y. T., & Kapuriya, N. P. (2021). Facile Synthesis of (E)-5-Styrylpyrimidines via Wittig Reaction Using Sodium Tripolyphosphate in Water. Letters in Organic Chemistry, 18(8), 634-639. en_US
dc.identifier.issn 1875-6255
dc.identifier.uri http://10.9.150.37:8080/dspace//handle/atmiyauni/862
dc.description We are thankful to the Department of Chemistry, Shree M. & N. Virani Science College (Autonomous) Rajkot, Bhakta Kavi Narsinh Mehta University, Junagadh, and Saurashtra University, Rajkot for providing necessary research and literature search facilities. The authors are also thankful to the “National Facility for Drug Discovery through NCE’s Development and Instrumentation Support to Small Manufacturing Pharma Enterprises” (NFDD) program under DPRS jointly funded by the Department of Science and Technology (DST) for spectral analysis. en_US
dc.description.abstract An inexpensive and eco-friendly Wittig olefination protocol has been developed to prepare novel (E)-5-styrylpyrimidines. The reaction of pyrimidine phosphonium ylide with different aryl/heteroaryl aldehydes underwent smoothly in the presence of sodium tripolyphosphate (STPP) in aqueous condition giving (E)-5-styrylpyrimidines (10a-t) in very high yields (77-96 %). en_US
dc.language.iso en en_US
dc.publisher Letters in Organic Chemistry, Bentham Science Publishers en_US
dc.subject Wittig reaction, (E)-5-styrylpyrimidines en_US
dc.subject sodium tripolyphosphate en_US
dc.subject water-mediated en_US
dc.subject green chemistry en_US
dc.title Facile synthesis of (E)-5-styrylpyrimidines via wittig reaction using sodium tripolyphosphate in water en_US
dc.type Article en_US


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