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Development of Nitromethane catalyzed C-H activation for the preparation of chromeno[3,4-d]imidazol-4-ones as hybrid scaffolds
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| dc.contributor.author | Jain, Vicky | |
| dc.contributor.author | Bijani, Sabera | |
| dc.contributor.author | Ambasana, Pratik | |
| dc.contributor.author | Bhoya, Umed | |
| dc.contributor.author | Shah, Anamik | |
| dc.date.accessioned | 2023-05-08T03:34:14Z | |
| dc.date.available | 2023-05-08T03:34:14Z | |
| dc.date.issued | 2015 | |
| dc.identifier.citation | Jain, V., Bijani, S., Ambasana, P., Bhoya, U., & Shah, A. (2015). Development of Nitromethane catalyzed CH activation for the preparation of chromeno [3, 4-d] imidazol-4-ones as hybrid scaffolds. Chemistry & Biology Interface, 5(6). | en_US |
| dc.identifier.issn | 2249-4820 | |
| dc.identifier.uri | http://10.9.150.37:8080/dspace//handle/atmiyauni/863 | |
| dc.description | The authors are thankful to funding agencies UGC (SAP) DRS-II & DSA-I, GOI, New Delhi, DST (FIST-II), GOI, New Delhi, National Facility for Drug Discovery Centre (DST-DPRP) and Centre of Excellence in Drug Discoveryd funded by Industries Commissionerate Gujarat (India). The authors are also thankful to Professor and Head at Department of Chemistry, Saurashtra University, Rajkot for providing facilities. | en_US |
| dc.description.abstract | Herein we report a tandem cyclization protocol towards hitherto unprepared hybrid scaffolds of coumarin and imidazole core. The synthetic methodology initiates with linking of aromatic amines with coumarin at 4-position, followed by tandem cyclization with the help of nitromethane leading to the synthesis of title compounds in high to excellent yields (80-97%). Detailed characterization including 1 H NMR, 13C NMR and HRMS for all newly synthesized compounds has been reported | en_US |
| dc.description.sponsorship | UGC(SAP) DRS-II & DSA-I, GOI, New Delhi, DST (FIST-II), GOI, New Delhi, National Facility for Drug Discovery Centre (DST-DPRP) | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Chemistry & Biology Interface | en_US |
| dc.subject | hybrid molecules | en_US |
| dc.subject | coumarin | en_US |
| dc.subject | tandem cyclization | en_US |
| dc.subject | nitromethane | en_US |
| dc.subject | imidazole | en_US |
| dc.title | Development of Nitromethane catalyzed C-H activation for the preparation of chromeno[3,4-d]imidazol-4-ones as hybrid scaffolds | en_US |
| dc.type | Article | en_US |
