Abstract:
The COVID-19 (Coronavirus Disease-19) is extremely contagious and quickly spreadable pathogenic viral
infection caused by SARS-CoV- 2, a virus belongs to coronavirus family member. It was appeared abruptly
in Wuhan, China; transmitted possibly from bat to human followed by human to human and now becomes
pandemic. The intermediate stage of transmission is not known but becomes a global challenge to stop the
spread of virus. The best way to avoid the chain of viral spread is suggested as isolation. Though, mutagenic
strains of this virus has been observed, the genome of virus has been sequenced that helps in development of
viral diagnosis kit. Vaccines has been developed in the vast genomic era and now the world is moving
towards direct human vaccine trial. The sensitivity of diagnostic kits, development of antiviral drugs and
vaccines can save the life. This review is focused on overall knowledge of viral origin, their genetics,
structure, diagnosis, precautions and possible therapy currently developed or under developmental progress
by scientist.
