An efficient, cleaner and environment benign Knoevenagel condensation of aromatic aldehydes with 3-methyl-5-pyrazolone using TEAB in water media is described. The reaction is highly chemoselective with no side reactions. The
procedure does not involve the use of any additional reagent/catalyst, produces no waste, and represents a green
synthetic protocol.
Description:
Authors are thankful for facilities & grants given
under UGC-SAP for Department Research Support
(DRS) and Department of Science & Technology (DST)
New Delhi for Fund for Improvement of Science &
Technology (FIST) and Department of Chemistry for
providing laboratory facilities.
